Efficacy of Oral Vaccine against Classical Swine Fever in Wild Boar and Estimation of the Disease Dynamics in the Quantitative Approach

Bazarragchaa, Enkhbold; Isoda, Norikazu; Kim, Taksoo; Tetsuo, Madoka; Ito, Satoshi; Matsuno, Keita; Sakoda, Yoshihiro

Efficacy of Oral Vaccine against Classical Swine Fever in Wild Boar and Estimation of the Disease Dynamics in the Quantitative Approach

Bazarragchaa, Enkhbold; Isoda, Norikazu; Kim, Taksoo et al.

Viruses-Basel, 2021, 13(2), 319

Permalink : https://hdl.handle.net/2115/81361

このアイテムのアクセス数:493件（2026-06-22 19:42 集計）

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論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/81361
タイトル	Efficacy of Oral Vaccine against Classical Swine Fever in Wild Boar and Estimation of the Disease Dynamics in the Quantitative Approach
著者	Bazarragchaa, Enkhbold ; Isoda, Norikazu ; Kim, Taksoo ; Tetsuo, Madoka ; Ito, Satoshi ; Matsuno, Keita ; Sakoda, Yoshihiro
著者名 Bazarragchaa, Enkhbold
e-Rad_Researcher 80615732 著者名 Isoda, Norikazu
著者名 Kim, Taksoo
著者名 Tetsuo, Madoka
著者名 Ito, Satoshi
e-Rad_Researcher 40753306 著者名 Matsuno, Keita
e-Rad_Researcher 40333637 著者名 Sakoda, Yoshihiro
言語	英語
キーワード	classical swine fever
	epidemiology
	oral vaccine
	wild boar
	quantitative analysis
発行日	2021-02-20
出版者	MDPI
収録物名	Viruses-Basel
巻(号)	13(2)
ページ	319
抄録	Classical swine fever virus (CSFV) in the wild boar population has been spreading in Japan, alongside outbreaks on pigs, since classical swine fever (CSF) reemerged in September 2018. The vaccination using oral bait vaccine was initially implemented in Gifu prefecture in March 2019. In the present study, antibodies against CSFV in wild boar were assessed in 1443 captured and dead wild boars in Gifu prefecture. After the implementation of oral vaccination, the increase of the proportion of seropositive animals and their titer in wild boars were confirmed. Quantitative analysis of antigen and antibodies against CSFV in wild boar implies potential disease diversity in the wild boar population. Animals with status in high virus replication (Ct < 30) and non- or low-immune response were confirmed and were sustained at a certain level after initial oral vaccination. Through continuous vaccination periods, the increase of seroprevalence among wild boar and the decrease of CSFV-positive animals were observed. The epidemiological analysis based on the quantitative virological outcomes could provide more information on the efficacy of oral vaccination and dynamics of CSF in the wild boar population, which will help to improve the implementation of control measures for CSF in countries such as Japan and neighboring countries.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.3390/v13020319