A cross-sectional exploratory survey on occurrence of triple-whammy prescription pattern in Japan

Imai, Shungo; Momo, Kenji; Kashiwagi, Hitoshi; Miyai, Takayuki; Sugawara, Mitsuru; Takekuma, Yoh

A cross-sectional exploratory survey on occurrence of triple-whammy prescription pattern in Japan

Imai, Shungo; Momo, Kenji; Kashiwagi, Hitoshi et al.

International Journal of Clinical Pharmacy, 2020, 42, 1369-1373

Permalink : https://hdl.handle.net/2115/82453

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アクセス権	open access
URI	https://hdl.handle.net/2115/82453
タイトル	A cross-sectional exploratory survey on occurrence of triple-whammy prescription pattern in Japan
著者	Imai, Shungo ; Momo, Kenji ; Kashiwagi, Hitoshi ; Miyai, Takayuki ; Sugawara, Mitsuru ; Takekuma, Yoh
e-Rad_Researcher 40845070 著者名 Imai, Shungo
著者名 Momo, Kenji
e-Rad_Researcher 60510609 著者名 Kashiwagi, Hitoshi
著者名 Miyai, Takayuki
e-Rad_Researcher 60332467 著者名 Sugawara, Mitsuru
e-Rad_Researcher 00396293 著者名 Takekuma, Yoh
言語	英語
キーワード	Acute kidney injury
	Insurance claims
	Japan
	Triple-whammy prescriptions
発行日	2020-08-17
出版者	Springer
収録物名	International Journal of Clinical Pharmacy
巻(号)	42
ページ	1369-1373
抄録	BackgroundThe concurrent use of nonsteroidal anti-inflammatory drugs, renin-angiotensin-aldosterone system blockers, and diuretics, known as a "triple-whammy," is related to the occurrence of acute kidney injury. However, there are few reports regarding the prescription pattern of the triple-whammy.ObjectiveTo elucidate the patterns of the triple-whammy prescription in Japan.MethodsA cross-sectional study was performed using a health-insurance-claims database that included Japanese people under 75 years of age, and enrolled outpatients that were prescribed any nonsteroidal anti-inflammatory drugs, renin-angiotensin-aldosterone system blockers, and diuretics between April 2017 and June 2017. As an outcome, the proportion of triple-whammy prescriptions was evaluated. Among the patients who received triple-whammy prescriptions, we evaluated the prevalence of chronic kidney disease and the proportion of prescriptions provided for these three drugs from different clinical departments and institutions.ResultsOverall, 730 of 246,721 (0.3%) patients received triple-whammy prescriptions. Among these patients, 13.3% had underlying chronic kidney disease. The proportions of any of the three drug types prescribed by different clinical departments and institutions was 48.2% and 61.8%, respectively.ConclusionsWe examined the patterns of triple-whammy prescriptions and concluded that pharmacists need to pay attention to triple-whammy prescriptions if the prescriptions are provided by multiple clinical departments or institutions.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	This is a post-peer-review, pre-copyedit version of an article published in International Journal of Clinical Pharmacy. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11096-020-01088-z.
PISSN	2210-7703
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1007/s11096-020-01088-z