Validation of Fully Automatic Quantitative Software for Finger Joint Space Narrowing Progression for Rheumatoid Arthritis Patients

Narisawa, Chiaki; Sutherland, Kenneth; Lu, Yutong et al.

Journal of digital imaging, 2020, 33(6), 1387-1392

Permalink : https://hdl.handle.net/2115/82767

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論文情報

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アクセス権
open access
URI
https://hdl.handle.net/2115/82767
タイトル
Validation of Fully Automatic Quantitative Software for Finger Joint Space Narrowing Progression for Rheumatoid Arthritis Patients
著者
Narisawa, Chiaki ; Sutherland, Kenneth ; Lu, Yutong ; Furusaki, Akira ; Sagawa, Akira ; Kamishima, Tamotsu
著者名
Narisawa, Chiaki
e-Rad_Researcher
30451446
著者名
Sutherland, Kenneth
著者名
Lu, Yutong
著者名
Furusaki, Akira
著者名
Sagawa, Akira
e-Rad_Researcher
10399868
著者名
Kamishima, Tamotsu
言語
英語
キーワード
Rheumatoid arthritis
Radiography
Joint space narrowing
Computer-based analysis
発行日
2020-09-28
出版者
Springer
収録物名
Journal of digital imaging
巻(号)
33(6)
ページ
1387-1392
抄録
In rheumatoid arthritis (RA), the radiographic progression of joint space narrowing (JSN) is evaluated using visual assessments. However, those methods are complicated and time-consuming. We developed an automatic system that can detect joint locations and compute the joint space difference index (JSDI), which was defined as the chronological change in JSN between two radiographs. The purpose of this study was to establish the validity of the software that automatically evaluates the temporal change of JSN. This study consisted of 39 patients with RA. All patients were treated with tocilizumab and underwent hand radiography (left and right hand separately) at 0, 6, and 12 months. The JSN was evaluated using mTSS (modified Total Sharp Score) by one musculoskeletal radiologist as well as our automatic system. Software measurement showed that JSDI between 0 and 12 months was significantly higher than that between 0 and 6 months (p< 0.01). While, there was no significant difference in mTSS between 0, 6, and 12 months. The group with higher disease activity at 0 months had significantly higher JSDI between 0 and 6 months than that with lower disease activity (p= 0.02). The automatic software can evaluate JSN progression of RA patients in the finger joint on X-ray.
資源タイプ
学術雑誌論文
出版タイプ
Accepted Manuscript
権利情報
This is a post-peer-review, pre-copyedit version of an article published in Journal of Digital Imaging. The final authenticated version is available online at: https://doi.org/10.1007/s10278-020-00390-6
PISSN
0897-1889
EISSN
1618-727X
関連情報 (isVersionOf)
出版社版DOI
https://doi.org/10.1007/s10278-020-00390-6