Aggravation of Ossified Ligamentum Flavum Lesion Is Associated With the Degree of Obesity

Endo, Tsutomu; Koike, Yoshinao; Hisada, Yuichiro; Fujita, Ryo; Suzuki, Ryota; Tanaka, Masaru; Tsujimoto, Takeru; Shimamura, Yukitoshi; Hasegawa, Yuichi; Kanayama, Masahiro; Yamada, Katsuhisa; Iwata, Akira; Sudo, Hideki; Ishii, Misaki; Iwasaki, Norimasa; Takahata, Masahiko

Aggravation of Ossified Ligamentum Flavum Lesion Is Associated With the Degree of Obesity

Endo, Tsutomu; Koike, Yoshinao; Hisada, Yuichiro et al.

Global Spine Journal, 2021, 13(5), 1325-1331

Permalink : https://hdl.handle.net/2115/83245

このアイテムのアクセス数:580件（2026-08-15 22:59 集計）

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https://doi.org/10.1177/21925682211031514			63

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アクセス権	open access
URI	https://hdl.handle.net/2115/83245
タイトル	Aggravation of Ossified Ligamentum Flavum Lesion Is Associated With the Degree of Obesity
著者	Endo, Tsutomu ; Koike, Yoshinao ; Hisada, Yuichiro ; Fujita, Ryo ; Suzuki, Ryota ; Tanaka, Masaru ; Tsujimoto, Takeru ; Shimamura, Yukitoshi ; Hasegawa, Yuichi ; Kanayama, Masahiro ; Yamada, Katsuhisa ; Iwata, Akira ; Sudo, Hideki ; Ishii, Misaki ; Iwasaki, Norimasa ; Takahata, Masahiko
e-Rad_Researcher 90805293 著者名 Endo, Tsutomu
著者名 Koike, Yoshinao
著者名 Hisada, Yuichiro
著者名 Fujita, Ryo
著者名 Suzuki, Ryota
著者名 Tanaka, Masaru
著者名 Tsujimoto, Takeru
著者名 Shimamura, Yukitoshi
著者名 Hasegawa, Yuichi
著者名 Kanayama, Masahiro
著者名 Yamada, Katsuhisa
e-Rad_Researcher 10374373 著者名 Iwata, Akira
e-Rad_Researcher 30374367 著者名 Sudo, Hideki
著者名 Ishii, Misaki
e-Rad_Researcher 30322803 著者名 Iwasaki, Norimasa
e-Rad_Researcher 40374368 著者名 Takahata, Masahiko
言語	英語
キーワード	severe obesity
	body mass index
	spinal ligament
	posterior longitudinal ligament
	thoracic
	ligamentum flavum
	ossification
発行日	2021-11-09
出版者	SAGE Publications
収録物名	Global Spine Journal
巻(号)	13(5)
ページ	1325-1331
抄録	Study Design: Retrospective cross-sectional study. Objectives: There is insufficient data on the clinical features of ossification of the ligamentum flavum (OLF) of the thoracic spine and the risk of progression of ossified lesions. The link between obesity and ossification of the posterior longitudinal ligament (OPLL), which frequently coexists with OLF, has been demonstrated. However, the link between obesity and OLF has not been recognized. We aimed to determine the prevalence of obesity in thoracic OLF and whether the severity of OLF is associated with the degree of obesity. Methods: A total of 204 symptomatic Japanese subjects with thoracic OLF and 136 subjects without spinal ligament ossification as controls were included. OLF subjects were divided into 3 groups: 1) localized OLF (OLF <2-intervertebral regions); 2) multilevel OLF (OLF >= 3-intervertebral regions); and 3) OLF + OPLL. The severity of OLF was quantified using the OLF index using computed tomography imaging of the entire spine. Results: The proportion of severely obese subjects (BMI >= 30 kg/m(2)) was significantly higher both in the multilevel OLF group (25.5%) and the OLF + OPLL group (44.3%) than in the localized OLF group (3.6%) and the control group (1.4%) (P < 0.01). BMI, age, and coexistence of cervical OPLL and lumbar OLF were associated with thoracic OLF index in the multiple regression analysis. Conclusions: Our findings demonstrated that obesity is a distinct feature of multilevel OLF in the thoracic spine and that the severity of OLF is associated with the degree of obesity.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
PISSN	2192-5682
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1177/21925682211031514