Pilot study using virtual 4-D tracking electromagnetic navigation bronchoscopy in the diagnosis of pulmonary nodules : a single center prospective study

Ishiwata, Tsukasa; Ujiie, Hideki; Gregor, Alexander et al.

Journal of Thoracic Disease, 2021, 13(5), 2885-2895

Permalink : https://hdl.handle.net/2115/83403

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アクセス権
open access
URI
https://hdl.handle.net/2115/83403
タイトル
Pilot study using virtual 4-D tracking electromagnetic navigation bronchoscopy in the diagnosis of pulmonary nodules : a single center prospective study
著者
Ishiwata, Tsukasa ; Ujiie, Hideki ; Gregor, Alexander ; Inage, Terunaga ; Motooka, Yamato ; Kinoshita, Tomonari ; Aragaki, Masato ; Chen, Zhenchian ; Effat, Andrew ; Bernards, Nicholas ; Yasufuku, Kazuhiro
著者名
Ishiwata, Tsukasa
著者名
Ujiie, Hideki
著者名
Gregor, Alexander
著者名
Inage, Terunaga
著者名
Motooka, Yamato
著者名
Kinoshita, Tomonari
著者名
Aragaki, Masato
著者名
Chen, Zhenchian
著者名
Effat, Andrew
著者名
Bernards, Nicholas
著者名
Yasufuku, Kazuhiro
言語
英語
キーワード
Electromagnetic navigation bronchoscopy
prospective study
4D tracking
diagnostic performance
発行日
2021-05
出版者
AME Publishing Company
収録物名
Journal of Thoracic Disease
巻(号)
13(5)
ページ
2885-2895
抄録
Background: Electromagnetic navigation bronchoscopy (ENB) is a navigation technology intended to improve the diagnostic yield of pulmonary nodules. However, nodule displacement due to respiratory motion may compromise the accuracy of the navigation guidance. The Veran SPiNDrive ENB system employs respiratory-gating (4D-tracking) to compensate for this motion. The aim of the present study was to evaluate the diagnostic performance and safety of the Veran SPiNDrive system for biopsy of pulmonary nodules. Methods: Adult patients with pulmonary nodules of ≥1 cm were enrolled at a single center. Both conventional bronchoscopy and 4D-tracking ENB were performed in one procedure session under general anesthesia, with the procedure order being randomly assigned. Radial probe endobronchial ultrasound and fluoroscopy were used in both groups. The diagnostic performance, safety, total procedure time, and total fluoroscopy time of the ENB phase were compared to the corresponding conventional bronchoscopy phase. Results: The study was terminated due to poor accrual; a total of eleven patients were enrolled. The mean size of pulmonary nodules was 2.1 cm. The sensitivity for malignancy was 67% (6/9) and 56% (5/9) with conventional bronchoscopy and with 4D-tracking ENB, respectively. Two cases developed minor bleeding after conventional bronchoscopy, while no complications were observed after 4D-tracking ENB. The mean procedure time was 16.1 and 21.7 min (P=0.090), and the mean duration time for fluoroscopy use was 77 and 44 sec (P=0.056) for the conventional bronchoscopy and the 4D-tracking ENB phases, respectively. Conclusions: The diagnostic performance of the Veran SPiNDrive 4D-tracking ENB did not exceed that of conventional bronchoscopy for pulmonary nodules. No complications were seen during 4D-tracking ENB. A study with a larger number of participants is required for further assessment.
資源タイプ
学術雑誌論文
出版タイプ
Version of Record
権利情報
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
PISSN
2072-1439
EISSN
2077-6624
関連情報 (isIdenticalTo)
出版社版DOI
https://doi.org/10.21037/jtd-21-141