Hepatitis E virus infection in pigs : a first report from Zambia

Chambaro, Herman M.; Sasaki, Michihito; Muleya, Walter et al.

Emerging microbes and infections, 2021, 10(1), 2169-2172

Permalink : https://hdl.handle.net/2115/83644

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https://doi.org/10.1080/22221751.2021.2002669     2

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アクセス権
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URI
https://hdl.handle.net/2115/83644
タイトル
Hepatitis E virus infection in pigs : a first report from Zambia
著者
Chambaro, Herman M. ; Sasaki, Michihito ; Muleya, Walter ; Kajihara, Masahiro ; Shawa, Misheck ; Mwape, Kabemba E. ; Harima, Hayato ; Qiu, Yongjin ; Hall, William W. ; Fandamu, Paul ; Squarre, David ; Simulundu, Edgar ; Sawa, Hirofumi ; Orba, Yasuko
著者名
Chambaro, Herman M.
e-Rad_Researcher
70609403
著者名
Sasaki, Michihito
著者名
Muleya, Walter
e-Rad_Researcher
70711894
著者名
Kajihara, Masahiro
著者名
Shawa, Misheck
著者名
Mwape, Kabemba E.
e-Rad_Researcher
70805407
著者名
Harima, Hayato
e-Rad_Researcher
00760985
著者名
Qiu, Yongjin
著者名
Hall, William W.
著者名
Fandamu, Paul
著者名
Squarre, David
著者名
Simulundu, Edgar
e-Rad_Researcher
30292006
著者名
Sawa, Hirofumi
e-Rad_Researcher
60507169
著者名
Orba, Yasuko
言語
英語
キーワード
Hepatitis E virus
genotype 3
seroprevalence
domestic pig
Zambia
発行日
2021-01-01
出版者
Taylor & Francis
収録物名
Emerging microbes and infections
巻(号)
10(1)
ページ
2169-2172
抄録
While evidence suggests presence of HEV infection in humans in Zambia, currently, there is no information on its occurrence in domestic pigs. Here, we investigated the presence of HEV antibodies and genome in domestic pigs in Zambia. Sera (n = 484) from domestic pigs were screened for antibodies against HEV by ELISA while genome detection in fecal (n = 25) and liver (n = 100) samples from slaughter pigs was conducted using nested RT-PCR assay. Overall, seroprevalence was 47.7% (231/484) while zoonotic genotype 3 HEV RNA was detected in 16.0% (20/125) of slaughtered pigs. This is the first report to highlight occurrence of HEV infection in domestic pigs in Zambia. This finding suggests possible contamination of the pork supply chain. Moreover, there is a potential risk of zoonotic transmission of HEV to abattoir workers, pig farmers and handlers.
資源タイプ
学術雑誌論文
出版タイプ
Version of Record
関連情報 (isIdenticalTo)
出版社版DOI
https://doi.org/10.1080/22221751.2021.2002669