open access

https://hdl.handle.net/2115/83738

Effect of trehalose supplementation in milk replacer on the incidence of diarrhea and fecal microbiota in preweaned calves

英語

trehalose

2021-01

Oxford University Press

Journal of animal science

99(1)

skab012

Trehalose, a nonreducing disaccharide consisting of D-glucose with alpha,alpha-1,1 linkage, was evaluated as a functional material to improve the gut environment in preweaned calves. In experiment 1, 173 calves were divided into two groups; the trehalose group was fed trehalose at 30 g/animal/d with milk replacer during the suckling period, and the control group was fed nonsupplemented milk replacer. Medication frequency was lower in the trehalose group (P < 0.05). In experiment 2, calves (n = 20) were divided into two groups (control group [n = 10] and trehalose group [n =10] based on their body weight and reared under the same feeding regimens as in experiment 1. Fresh feces were collected from individual animals at the beginning of the trial (average age 11 d), 3 wk after trehalose feeding (experimental day 22), and 1 d before weaning, and the fecal score was recorded daily. Fecal samples were analyzed for fermentation parameters and microbiota. The fecal score was significantly lower in the trehalose group than in the control group in the early stage (at an age of 14 to 18 d; P < 0.05) of the suckling period. Calves fed trehalose tended to have a higher proportion of fecal butyrate on day 22 than calves in the control group (P = 0.08). Population sizes of Clostridium spp. were significantly lower (P = 0.036), whereas those of Dialister spp. and Eubacterium spp. tended to be higher in the feces of calves in the trehalose group on day 22 (P = 0.060 and P = 0.083). These observations indicate that trehalose feeding modulated the gut environment and partially contributed to the reduction in medication frequency observed in experiment 1.

学術雑誌論文

Accepted Manuscript

This is a pre-copyedited, author-produced version of an article accepted for publication in Journal of Animal Science following peer review. The version of record Hiroto Miura, Kazuhisa Mukai, Keigo Sudo, Satoshi Haga, Yutaka Suzuki, Yasuo Kobayashi, Satoshi Koike, Effect of trehalose supplementation in milk replacer on the incidence of diarrhea and fecal microbiota in preweaned calves, Journal of Animal Science, Volume 99, Issue 1, January 2021, skab012, is available online at: https://doi.org/10.1093/jas/skab012.

0021-8812