Serological methods for detection of infection with shrew-borne hantaviruses : Thottapalayam, Seewis, Altai, and Asama viruses

Wei, Zhouoxing; Shimizu, Kenta; Nishigami, Kumpei et al.

Archives of virology, 2021, 166, 275-280

Permalink : https://hdl.handle.net/2115/83794

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論文情報

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アクセス権
open access
URI
https://hdl.handle.net/2115/83794
タイトル
Serological methods for detection of infection with shrew-borne hantaviruses : Thottapalayam, Seewis, Altai, and Asama viruses
著者
Wei, Zhouoxing ; Shimizu, Kenta ; Nishigami, Kumpei ; Tsuda, Yoshimi ; Sarathukumara, Yomani ; Muthusinghe, Devinda S. ; Gamage, Chandika D. ; Granathne, Lishanta ; Lokupathirage, Sithumini M. W. ; Nanayakkara, Nishanta ; Arikawa, Jiro ; Kikuchi, Fuka ; Tanaka-Taya, Keiko ; Suzuki, Motoi ; Morikawa, Shigeru ; Arai, Satoru ; Yoshimatsu, Kumiko
著者名
Wei, Zhouoxing
e-Rad_Researcher
20466840
著者名
Shimizu, Kenta
著者名
Nishigami, Kumpei
著者名
Tsuda, Yoshimi
著者名
Sarathukumara, Yomani
著者名
Muthusinghe, Devinda S.
著者名
Gamage, Chandika D.
著者名
Granathne, Lishanta
著者名
Lokupathirage, Sithumini M. W.
著者名
Nanayakkara, Nishanta
e-Rad_Researcher
10142704
著者名
Arikawa, Jiro
著者名
Kikuchi, Fuka
著者名
Tanaka-Taya, Keiko
著者名
Suzuki, Motoi
e-Rad_Researcher
00167686
著者名
Morikawa, Shigeru
e-Rad_Researcher
80321868
著者名
Arai, Satoru
e-Rad_Researcher
90220722
著者名
Yoshimatsu, Kumiko
言語
英語
発行日
2021-01
出版者
Springer
収録物名
Archives of virology
巻(号)
166
ページ
275-280
抄録
The infectivity of shrew-borne hantaviruses to humans is still unclear because of the lack of a serodiagnosis method for these viruses. In this study, we prepared recombinant nucleocapsid (rN) proteins of Seewis orthohantavirus, Altai orthohantavirus (ALTV), Thottapalayam thottimvirus (TPMV), and Asama orthohantavirus. Using monospecific rabbit sera, no antigenic cross-reactivity was observed. In a serosurvey of 104 samples from renal patients and 271 samples from heathy controls from Sri Lanka, one patient serum and two healthy control sera reacted with rN proteins of ALTV and TPMV, respectively. The novel assays should be applied to investigate potential infectivity of shrew-borne hantaviruses to humans.
資源タイプ
学術雑誌論文
出版タイプ
Accepted Manuscript
権利情報
This is a post-peer-review, pre-copyedit version of an article published in Archives of Virology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00705-020-04873-3
PISSN
0304-8608
関連情報 (isVersionOf)
出版社版DOI
https://doi.org/10.1007/s00705-020-04873-3