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https://hdl.handle.net/2115/84371

Body Mass Index can Similarly Predict the Presence of Multiple Cardiovascular Risk Factors in Middle-aged Japanese Subjects as Waist Circumference

英語

middle-aged Japanese subjects

2010-06-01

The Japanese Society of Internal Medicine (日本内科学会)

Internal Medicine

49(11)

977-982

ObjectiveAdiposity is closely associated with the clustering of metabolic risk factors such as high bloodpressure, dyslipidemia, and glucose intolerance. Waist circumference and body mass index (BMI) are the es-tablished markers of abdominal adiposity and general adiposity, respectively. However, it has not been exam-ined whether these two markers can detect the clustering of metabolic risk factors in Japanese subjects.Methods and ResultsWe studied 5,796 Japanese middle-aged subjects aged 40-60 years (4,344 males and1,452 females). Metabolic risk factors including highblood pressure, dyslipidemia, and glucose intolerancewere identified according to the diagnostic criteria for metabolic syndrome in Japan. The number of meta-bolic risk factors was significantly associated withthe BMI values in both male and female subjects. Theprevalence of subjects with multiple (two or more) metabolic risk factors was 29.4% and 7.6% in males andfemales, respectively. According to receiver operating characteristic (ROC) analysis, the area under curve val-ues of BMI and waist circumference did not differ in male (0.658 vs. 0.671, p=n.s.) and female (0.776 vs.0.790, p=n.s.) subjects, indicating that the waist circumference as well as the BMI could be useful in detect-ing the occurrence of multiple metabolic risk factors. The appropriate cut-off values of BMI to predict thepresence of multiple metabolic risk factors were 24.7 and 23.4 kg/m2in males and females, respectively. Thesensitivity and specificity using these cut-off values were 58 and 65% in males and 65 and 77% in females,respectively.ConclusionThe BMI values can similarly predict the presence of multiple metabolic risk factors just as thewaist circumference in Japanese middle-aged subjects.

学術雑誌論文

Version of Record

0918-2918

1349-7235