Development of new diacrylate monomers as substitutes for Bis-GMA and UDMA

Yoshinaga, Kazuhiko; Yoshihara, Kumiko; Yoshida, Yasuhiro

Development of new diacrylate monomers as substitutes for Bis-GMA and UDMA

Yoshinaga, Kazuhiko; Yoshihara, Kumiko; Yoshida, Yasuhiro

Dental materials, 2021, 37(6), E391-E398

Permalink : https://hdl.handle.net/2115/84445

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アクセス権	open access
URI	https://hdl.handle.net/2115/84445
タイトル	Development of new diacrylate monomers as substitutes for Bis-GMA and UDMA
著者	Yoshinaga, Kazuhiko ; Yoshihara, Kumiko ; Yoshida, Yasuhiro
著者名 Yoshinaga, Kazuhiko
著者名 Yoshihara, Kumiko
e-Rad_Researcher 90281162 著者名 Yoshida, Yasuhiro
言語	英語
キーワード	Dental monomer
	Bending test
	High-strength dental materials
	Diacrylate monomer
	Urethane acrylates
	Composite resin
	Light-curing resins
発行日	2021-06
出版者	Elsevier
収録物名	Dental materials
巻(号)	37(6)
ページ	E391-E398
抄録	Objective. Bisphenol A-glycidyl methacrylate (Bis-GMA) and urethane dimethacrylate (UDMA) are widely used as the primary components of (meth)acrylic monomers. However, the use of Bis-GMA, which is a bisphenol A derivative, in dentistry is being questioned after bisphenol A was found to exhibit estrogenic activity. Although UDMA is being considered as a substitute for bis-GMA, the mechanical properties of cured resin composites containing UDMA are less than desirable. Therefore, in this study, we developed new alternative (meth)acrylic monomers to enhance the mechanical strength of cured composite resins. Methods. Five urethane acrylic monomers were synthesized in this study as (meth)acrylic monomer substituents to replace Bis-GMA and UDMA. The elastic modulus, strength, and breaking energy values of cured resins consisting of mixtures of the urethane acrylates and diluting monomers were determined using the three-point flexural test. The data obtained were analyzed using one-way ANOVA and the post-hoc Tukey HSD tests (p < 0.05). Viscosities of the urethane acrylic monomers were measured with a cone-plate viscometer. Refractive indices of the urethane acrylic monomers were determined with an Abbe refractometer. Results. The results of the three-point flexural tests revealed that the cured urethane acrylic monomer-based resin exhibited higher elastic modulus (up to 40%) and strength (up to 21%) compared to the cured UDMA-based resin. Viscosity and refractive index of the urethane acrylic monomers were between those of UDMA and Bis-GMA. Significance. The developed urethane diacrylates prepared from diisocyanates which have an aromatic or aliphatic ring, 1,3-bis(1-isocyanato-1-methylethyl)benzene (TMXDI), 1,3-bis(isocyanatomethyl)benzene (XDI), or norbornane diisocyanate (NBDI) are worth considering as alternative options of Bis-GMA and UDMA for restorative resin composites. (c) 2021 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
権利情報	© 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
PISSN	0109-5641
関連情報	PMID 33757654
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.dental.2021.02.023