A simulation-based study on water radiolysis species for H-1(+), He-4(2+), and C-12(6+) ion beams with multiple ionization using Geant4-DNA

Baba, Kentaro; Kusumoto, Tamon; Okada, Shogo; Ishikawa, Masayori

A simulation-based study on water radiolysis species for H-1(+), He-4(2+), and C-12(6+) ion beams with multiple ionization using Geant4-DNA

Baba, Kentaro; Kusumoto, Tamon; Okada, Shogo et al.

Journal of Applied Physics, 2021, 129(24), 244702

Permalink : https://hdl.handle.net/2115/86158

このアイテムのアクセス数:375件（2026-01-18 16:18 集計）

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アクセス権	open access
URI	https://hdl.handle.net/2115/86158
タイトル	A simulation-based study on water radiolysis species for H-1(+), He-4(2+), and C-12(6+) ion beams with multiple ionization using Geant4-DNA
著者	Baba, Kentaro ; Kusumoto, Tamon ; Okada, Shogo ; Ishikawa, Masayori
著者名 Baba, Kentaro
e-Rad_Researcher 90825499 著者名 Kusumoto, Tamon
e-Rad_Researcher 40731732 著者名 Okada, Shogo
e-Rad_Researcher 80314772 著者名 Ishikawa, Masayori
言語	英語
発行日	2021-06-28
出版者	American Institute of Physics (AIP)
収録物名	Journal of Applied Physics
巻(号)	129(24)
ページ	244702
抄録	Monte Carlo track structure simulation is a powerful method for estimating damage induced by water radiolysis products for cell killing. To investigate the influence of multiple ionization for the formation of water radiolysis products under H-1(+), He-4(2+), and C-12(6+) ion beams, a Monte Carlo simulation based on Geant4-DNA was carried out. The G-value of H2O2 increased monotonically with increasing linear energy transfer up to 200 eV/nm. Above 200 eV/nm, the G-value of H2O2 began dropping, but only when the influence of multiple ionization was considered. This trend is in good agreement with the experimental results. Furthermore, we successfully reproduce the experimental results of G-values of HO2 center dot + O-2(center dot-). The role of the multiple ionization in the production of H2O2, HO2 center dot, O-2(center dot-), and O-2 is also discussed.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in "Baba, K. Kusumoto, T. Okada, S. Ishikawa, M. A simulation-based study on water radiolysis species for H-1(+), He-4(2+), and C-12(6+) ion beams with multiple ionization using Geant4-DNA. Journal of Applied Physics. 2021 129(24) 244702" and may be found at https://doi.org/10.1063/5.0054665
PISSN	0021-8979
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1063/5.0054665