Novel symbionts and potential human pathogens excavated from argasid tick microbiomes that are shaped by dual or single symbiosis

Moustafa, Mohamed Abdallah Mohamed; Mohamed, Wessam Mohamed Ahmed; Lau, Alice C. C.; Chatanga, Elisha; Qiu, Yongjin; Hayashi, Naoki; Naguib, Doaa; Sato, Kozue; Takano, Ai; Matsuno, Keita; Nonaka, Nariaki; Taylor, DeMar; Kawabata, Hiroki; Nakao, Ryo

Novel symbionts and potential human pathogens excavated from argasid tick microbiomes that are shaped by dual or single symbiosis

Moustafa, Mohamed Abdallah Mohamed; Mohamed, Wessam Mohamed Ahmed; Lau, Alice C. C. et al.

Computational and Structural Biotechnology Journal, 2022, 20, 1979-1992

Permalink : https://hdl.handle.net/2115/86242

このアイテムのアクセス数:617件（2026-08-17 14:43 集計）

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https://doi.org/10.1016/j.csbj.2022.04.020			32

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アクセス権	open access
URI	https://hdl.handle.net/2115/86242
タイトル	Novel symbionts and potential human pathogens excavated from argasid tick microbiomes that are shaped by dual or single symbiosis
著者	Moustafa, Mohamed Abdallah Mohamed ; Mohamed, Wessam Mohamed Ahmed ; Lau, Alice C. C. ; Chatanga, Elisha ; Qiu, Yongjin ; Hayashi, Naoki ; Naguib, Doaa ; Sato, Kozue ; Takano, Ai ; Matsuno, Keita ; Nonaka, Nariaki ; Taylor, DeMar ; Kawabata, Hiroki ; Nakao, Ryo
著者名 Moustafa, Mohamed Abdallah Mohamed
著者名 Mohamed, Wessam Mohamed Ahmed
著者名 Lau, Alice C. C.
著者名 Chatanga, Elisha
e-Rad_Researcher 00760985 著者名 Qiu, Yongjin
著者名 Hayashi, Naoki
著者名 Naguib, Doaa
著者名 Sato, Kozue
著者名 Takano, Ai
e-Rad_Researcher 40753306 著者名 Matsuno, Keita
e-Rad_Researcher 50281853 著者名 Nonaka, Nariaki
著者名 Taylor, DeMar
著者名 Kawabata, Hiroki
e-Rad_Researcher 50633955 著者名 Nakao, Ryo
言語	英語
キーワード	Argasid ticks
	Dual symbiosis
	Infection
	Pathogens
	Vector-borne diseases
発行日	2022-04-27
出版者	Elsevier
収録物名	Computational and Structural Biotechnology Journal
巻(号)	20
ページ	1979-1992
抄録	Research on vector-associated microbiomes has been expanding due to increasing emergence of vector borne pathogens and awareness of the importance of symbionts in the vector physiology. However, little is known about microbiomes of argasid (or soft-bodied) ticks due to limited access to specimens. We collected four argasid species (Argas japonicus, Carios vespertilionis, Ornithodoros capensis, and Ornithodoros sawaii) from the nests or burrows of their vertebrate hosts. One laboratory-reared argasid species (Ornithodoros moubata) was also included. Attempts were then made to isolate and characterize potential symbionts/pathogens using arthropod cell lines. Microbial community structure was distinct for each tick species. Coxiella was detected as the predominant symbiont in four tick species where dual symbiosis between Coxiella and Rickettsia or Coxiella and Francisella was observed in C. vespertilionis and O. moubata, respectively. Of note, A. japonicus lacked Coxiella and instead had Occidentia massiliensis and Thiotrichales as alternative symbionts. Our study found strong correlation between tick species and life stage. We successfully isolated Oc. massiliensis and characterized potential pathogens of genera Ehrlichia and Borrelia. The results suggest that there is no consistent trend of microbiomes in relation to tick life stage that fit all tick species and that the final interpretation should be related to the balance between environmental bacterial exposure and endosymbiont ecology. Nevertheless, our findings provide insights on the ecology of tick microbiomes and basis for future investigations on the capacity of argasid ticks to carry novel pathogens with public health importance. (c) 2022 The Author(s). Published by Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology. This is an open access article under the CC BY license (http://creativecommons. org/licenses/by/4.0/).
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
PISSN	2001-0370
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1016/j.csbj.2022.04.020