Features of accelerator-based neutron source for boron neutron capture therapy calculated by particle and heavy ion transport code system (PHITS)

Matsuya, Yusuke; Kusumoto, Tamon; Yachi, Yoshie; Hirata, Yuho; Miwa, Misako; Ishikawa, Masayori; Date, Hiroyuki; Iwamoto, Yosuke; Matsuyama, Shigeo; Fukunaga, Hisanori

Features of accelerator-based neutron source for boron neutron capture therapy calculated by particle and heavy ion transport code system (PHITS)

Matsuya, Yusuke; Kusumoto, Tamon; Yachi, Yoshie et al.

AIP Advances, 2022, 12(2), 025013

Permalink : https://hdl.handle.net/2115/86319

このアイテムのアクセス数:465件（2026-10-12 11:52 集計）

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https://doi.org/10.1063/5.0077782			43

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アクセス権	open access
URI	https://hdl.handle.net/2115/86319
タイトル	Features of accelerator-based neutron source for boron neutron capture therapy calculated by particle and heavy ion transport code system (PHITS)
著者	Matsuya, Yusuke ; Kusumoto, Tamon ; Yachi, Yoshie ; Hirata, Yuho ; Miwa, Misako ; Ishikawa, Masayori ; Date, Hiroyuki ; Iwamoto, Yosuke ; Matsuyama, Shigeo ; Fukunaga, Hisanori
e-Rad_Researcher 20826929 著者名 Matsuya, Yusuke
著者名 Kusumoto, Tamon
著者名 Yachi, Yoshie
著者名 Hirata, Yuho
著者名 Miwa, Misako
e-Rad_Researcher 80314772 著者名 Ishikawa, Masayori
e-Rad_Researcher 10197600 著者名 Date, Hiroyuki
著者名 Iwamoto, Yosuke
著者名 Matsuyama, Shigeo
e-Rad_Researcher 50781267 著者名 Fukunaga, Hisanori
言語	英語
発行日	2022-02-10
出版者	AIP Publishing
収録物名	AIP Advances
巻(号)	12(2)
ページ	025013
抄録	Accelerator-based neutron sources have been developed and installed in recent decades for boron neutron capture therapy (BNCT) in several clinical facilities. Lithium is one of the targets that can produce epithermal neutrons from the Li-7(p,n)Be-7 near-threshold reaction, and accelerator-based BNCT systems employing a Li target are promising for cancer treatment. The accurate evaluation of the characteristics of an accelerator-based neutron source is a key to estimating the therapeutic effects of the accelerator-based BNCT. Particle and Heavy Ion Transport code System (PHITS) is a general-purpose Monte Carlo code, which can simulate a variety of diverse particle types and nuclear reactions. The latest PHITS code enables simulating the generation of neutrons from the Li-7(p,n)Be-7 reactions by using the Japanese Evaluated Nuclear Data Library 4.0 high-energy file. Thus, the PHITS code can be adopted for dose estimation during treatment planning for the accelerator-based BNCT. In this study, we evaluated the neutron fluence using the PHITS code by comparing it to reference data. The subsequent neutron transport simulations were performed to evaluate the boron trifluoride detector responses and the recoiled proton fluence detected by a CR-39 plastic detector. These comparative studies confirmed that the PHITS code can accurately simulate neutrons generated from an accelerator using a Li target. The PHITS code has a significant potential for a detailed evaluation of neutron fields and for predicting the therapeutic effects of the accelerator-based BNCT.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
EISSN	2158-3226
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1063/5.0077782