Fabrication and cell behavior assessment of antibacterial micro/nano-patterned chitosan films

Nishida, Erika; Miyaji, Hirofumi; Sugaya, Tsutomu et al.

Nano Biomedicine, 2022, 14(1), 1-8

Permalink : https://hdl.handle.net/2115/86856

このアイテムのアクセス数:294件（2026-01-16 15:58 集計）

ファイル	フォーマット	サイズ	閲覧回数	説明
2022 Nishida Nano Biome	pdf	2.06 MB	163

アクセス権	open access
URI	https://hdl.handle.net/2115/86856
タイトル	Fabrication and cell behavior assessment of antibacterial micro/nano-patterned chitosan films
著者	Nishida, Erika ; Miyaji, Hirofumi ; Sugaya, Tsutomu ; Akasaka, Tsukasa
e-Rad_Researcher 50779882 著者名 Nishida, Erika
e-Rad_Researcher 50372256 著者名 Miyaji, Hirofumi
e-Rad_Researcher 10211301 著者名 Sugaya, Tsutomu
e-Rad_Researcher 00360917 著者名 Akasaka, Tsukasa
言語	英語
キーワード	biomaterial surfaces
	chitosan
	Streptococcus mutans
	MC3T3-E1 cell
発行日	2022-06
収録物名	Nano Biomedicine
巻(号)	14(1)
ページ	1-8
抄録	The surface of biomaterials with a fine micro/nano-pattern reportedly affects cell behavior. Chitosan was previously shown to exhibit antibacterial properties and thus here we evaluated the cellular response and antibacterial activity of chitosan micro/nano patterns prepared by the imprint method. We fabricated micro/nano patterns with different sizes and shapes of pillars, grooves, and holes. The chitosan pattern films exhibited antibacterial activity towards Streptococcus mutans. In addition, we observed mammalian cells adhering to and spreading on the chitosan pattern, and found that the orientation of the cells was controlled by the shape of the pattern.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
PISSN	1883-5198
NCID	AA12510316
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.11344/nano.14.1