Salivary Biomarker Profiles and Chronic Fatigue among Nurses Working Rotation Shifts : An Exploratory Pilot Study

Yamaguchi, Shinya; Watanabe, Kazuhiro; Sugimura, Naotaka et al.

Healthcare, 2022, 10(8), 1416

Permalink : https://hdl.handle.net/2115/86870

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https://doi.org/10.3390/healthcare10081416     103

論文情報

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アクセス権
open access
URI
https://hdl.handle.net/2115/86870
タイトル
Salivary Biomarker Profiles and Chronic Fatigue among Nurses Working Rotation Shifts : An Exploratory Pilot Study
著者
Yamaguchi, Shinya ; Watanabe, Kazuhiro ; Sugimura, Naotaka ; Shishido, Inaho ; Konya, Issei ; Fujita, Tomoko ; Yoshimitsu, Yuichi ; Kato, Shintaro ; Ito, Yoichi M. ; Yano, Rika
著者名
Yamaguchi, Shinya
著者名
Watanabe, Kazuhiro
著者名
Sugimura, Naotaka
e-Rad_Researcher
50911210
著者名
Shishido, Inaho
著者名
Konya, Issei
著者名
Fujita, Tomoko
著者名
Yoshimitsu, Yuichi
著者名
Kato, Shintaro
e-Rad_Researcher
10334236
著者名
Ito, Yoichi M.
e-Rad_Researcher
50250519
著者名
Yano, Rika
言語
英語
キーワード
nurses
fatigue
saliva
biomarkers
shift work schedule
発行日
2022-07-28
出版者
MDPI
収録物名
Healthcare
巻(号)
10(8)
ページ
1416
抄録
Although nurses' fatigue affects their well-being and patient safety, no effective objective measurements exist. We explored the profiles of salivary biomarkers associated with nurses' chronic fatigue across several shifts. This longitudinal study involved 45 shiftwork nurses and collected their saliva samples before two night and two day shifts for a month. Chronic fatigue was measured using the Cumulative Fatigue Symptom Index before the first night shift. Biomarker profiles were analyzed using hierarchical cluster analysis, and chronic fatigue levels were compared between the profiles. Cortisol profiles were classified into high- and low-level groups across two day shifts; the low-level group presented significantly higher irritability and unwillingness to work. Secretory immunoglobulin A (s-IgA) profiles across the four shifts were classified into high- and low-level groups; the high-level group had significantly higher depressive feelings, decreased vitality, irritability, and unwillingness to work. Cortisol (two day shifts) and s-IgA (four shifts) profiles were combined, and (i) cortisol low-level and s-IgA high-level and (ii) cortisol high-level and s-IgA low-level groups were identified. The former group had significantly higher chronic fatigue sign and irritability than the latter group. The profiles of salivary cortisol and s-IgA across several shifts were associated with nurses' chronic fatigue.
資源タイプ
学術雑誌論文
出版タイプ
Version of Record
関連情報
PMID
36011073
関連情報 (isIdenticalTo)
出版社版DOI
https://doi.org/10.3390/healthcare10081416