Phosphorus flame retardants in indoor dust and their relation to asthma and allergies of inhabitants

Araki, A.; Saito, I.; Kanazawa, A.; Morimoto, K.; Nakayama, K.; Shibata, E.; Tanaka, M.; Takigawa, T.; Yoshimura, T.; Chikara, H.; Saijo, Y.; Kishi, R.

Phosphorus flame retardants in indoor dust and their relation to asthma and allergies of inhabitants

Araki, A.; Saito, I.; Kanazawa, A. et al.

Indoor Air, 2014, 24(1), 3-15

Permalink : https://hdl.handle.net/2115/87333

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アクセス権	open access
URI	https://hdl.handle.net/2115/87333
タイトル	Phosphorus flame retardants in indoor dust and their relation to asthma and allergies of inhabitants
著者	Araki, A. ; Saito, I. ; Kanazawa, A. ; Morimoto, K. ; Nakayama, K. ; Shibata, E. ; Tanaka, M. ; Takigawa, T. ; Yoshimura, T. ; Chikara, H. ; Saijo, Y. ; Kishi, R.
e-Rad_Researcher 00619885 著者名 Araki, A.
著者名 Saito, I.
著者名 Kanazawa, A.
著者名 Morimoto, K.
著者名 Nakayama, K.
著者名 Shibata, E.
著者名 Tanaka, M.
著者名 Takigawa, T.
著者名 Yoshimura, T.
著者名 Chikara, H.
著者名 Saijo, Y.
e-Rad_Researcher 80112449 著者名 Kishi, R.
言語	英語
キーワード	Phosphorus flame retardants
	Organophosphate triesters
	Indoor dust
	Dwellings
	Asthma
	Allergy
発行日	2014-02
出版者	John Wiley & Sons
収録物名	Indoor Air
巻(号)	24(1)
ページ	3-15
抄録	Organophosphate esters are used as additives in flame retardants and plasticizers, and they are ubiquitous in the indoor environment. Phosphorus flame retardants (PFRs) are present in residential dust, but few epidemiological studies have assessed their impact on human health. We measured the levels of 11 PFRs in indoor floor dust and multi-surface dust in 182 single-family dwellings in Japan. We evaluated their correlations with asthma and allergies of the inhabitants. Tris(2-butoxyethyl) phosphate was detected in all samples (median value: 580 μg/g in floor dust, 111 μg/g in multi-surface dust). Tris(2-chloro-iso-propyl) phosphate (TCIPP) was detected at 8.69 μg/g in floor dust and 25.8 μg/g in multi-surface dust. After adjustment for potential confounders, significant associations were found between the prevalence of atopic dermatitis and the presence of TCIPP and tris(1,3-dichloro-2-propyl) phosphate in floor dust [per log10-unit, odds ratio (OR): 2.43 and 1.84, respectively]. Tributyl phosphate was significantly associated with the prevalence of asthma (OR: 2.85 in floor dust, 5.34 in multi-surface dust) and allergic rhinitis (OR: 2.55 in multi-surface dust). PFR levels in Japan were high compared with values reported previously for Europe, Asia-Pacific, and the USA. Higher levels of PFRs in house dust were related to the inhabitants' health status.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	This is the pre-peer-reviewed version of the following article: Araki, A., Saito, I., Kanazawa, A., Morimoto, K., Nakayama, K., Shibata, E., Tanaka, M., Takigawa, T., Yoshimura, T., Chikara, H., Saijo, Y. and Kishi, R. (2014), Phosphorus flame retardants in indoor dust and their relation to asthma and allergies of inhabitants. Indoor Air, 24: 3-15 which has been published in final form at https://doi.org/10.1111/ina.12054
PISSN	0905-6947
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1111/ina.12054