Relationship between adrenal steroid hormones in cord blood and birth weight : The Sapporo Cohort, Hokkaido Study on Environment and Children's Health

Mitsui, Takahiko; Araki, Atsuko; Goudarzi, Houman; Miyashita, Chihiro; Ito, Sachiko; Sasaki, Seiko; Kitta, Takeya; Moriya, Kimihiko; Cho, Kazutoshi; Morioka, Keita; Kishi, Reiko; Shinohara, Nobuo; Takeda, Masayuki; Nonomura, Katsuya

Relationship between adrenal steroid hormones in cord blood and birth weight : The Sapporo Cohort, Hokkaido Study on Environment and Children's Health

Mitsui, Takahiko; Araki, Atsuko; Goudarzi, Houman et al.

American Journal of Human Biology, 2018, 30(4), e23127

Permalink : https://hdl.handle.net/2115/87338

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アクセス権	open access
URI	https://hdl.handle.net/2115/87338
タイトル	Relationship between adrenal steroid hormones in cord blood and birth weight : The Sapporo Cohort, Hokkaido Study on Environment and Children's Health
著者	Mitsui, Takahiko ; Araki, Atsuko ; Goudarzi, Houman ; Miyashita, Chihiro ; Ito, Sachiko ; Sasaki, Seiko ; Kitta, Takeya ; Moriya, Kimihiko ; Cho, Kazutoshi ; Morioka, Keita ; Kishi, Reiko ; Shinohara, Nobuo ; Takeda, Masayuki ; Nonomura, Katsuya
著者名 Mitsui, Takahiko
e-Rad_Researcher 00619885 著者名 Araki, Atsuko
著者名 Goudarzi, Houman
e-Rad_Researcher 70632389 著者名 Miyashita, Chihiro
e-Rad_Researcher 90580936 著者名 Ito, Sachiko
著者名 Sasaki, Seiko
著者名 Kitta, Takeya
著者名 Moriya, Kimihiko
e-Rad_Researcher 10312365 著者名 Cho, Kazutoshi
著者名 Morioka, Keita
e-Rad_Researcher 80112449 著者名 Kishi, Reiko
e-Rad_Researcher 90250422 著者名 Shinohara, Nobuo
著者名 Takeda, Masayuki
e-Rad_Researcher 60113750 著者名 Nonomura, Katsuya
言語	英語
発行日	2018-07
出版者	John Wiley & Sons
収録物名	American Journal of Human Biology
巻(号)	30(4)
ページ	e23127
抄録	Objectives: We investigated the relationship between steroid hormone levels in cord blood and birth weight. Methods: Among 514 participants in a prospective birth cohort study in Sapporo, the following hormone levels were measured in 294 stored cord blood samples from 135 males and 159 females: androstenedione, dehydroepiandrosterone (DHEA), cortisol, and cortisone. Birth weight information was obtained from medical records. Results: Androstenedione/DHEA was significantly higher in males than in females, while DHEA was significantly higher in females. Birth weight was significantly higher in males than in females. Regarding cortisone, androstenedione/DHEA, and cortisone/cortisol, a correlation was observed with birth weight in males but not in females. Conclusions: Prenatal adrenal steroids as well as converting enzymes such as 11ß-hydrosteroid dehydrogenase type 2 and 3ß-hydrosteroid dehydrogenase may have an impact on prenatal physical development.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	This is the peer reviewed version of the following article: Mitsui, T, Araki, A, Goudarzi, H, et al. Relationship between adrenal steroid hormones in cord blood and birth weight: The Sapporo Cohort, Hokkaido Study on Environment and Children's Health. Am J Hum Biol. 2018; 30:e23127, which has been published in final form at https://doi.org/10.1002/ajhb.23127. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
PISSN	1042-0533
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1002/ajhb.23127