Signal transducer and activator of transcription 3 regulation by novel binding partners.

Matsuda, Tadashi; Muromoto, Ryuta; Sekine, Yuichi; Togi, Sumihito; Kitai, Yuichi; Kon, Shigeyuki; Oritani, Kenji

Signal transducer and activator of transcription 3 regulation by novel binding partners.

Matsuda, Tadashi; Muromoto, Ryuta; Sekine, Yuichi et al.

World journal of biological chemistry, 2015, 6(4), 324-332

Permalink : https://hdl.handle.net/2115/87688

このアイテムのアクセス数:223件（2026-03-04 21:02 集計）

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論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/87688
タイトル	Signal transducer and activator of transcription 3 regulation by novel binding partners.
著者	Matsuda, Tadashi ; Muromoto, Ryuta ; Sekine, Yuichi ; Togi, Sumihito ; Kitai, Yuichi ; Kon, Shigeyuki ; Oritani, Kenji
e-Rad_Researcher 20212219 著者名 Matsuda, Tadashi
e-Rad_Researcher 30455597 著者名 Muromoto, Ryuta
e-Rad_Researcher 20396295 著者名 Sekine, Yuichi
著者名 Togi, Sumihito
e-Rad_Researcher 90756165 著者名 Kitai, Yuichi
e-Rad_Researcher 90344499 著者名 Kon, Shigeyuki
e-Rad_Researcher 70324762 著者名 Oritani, Kenji
言語	英語
キーワード	Janus kinase/signal transducer and activator of transcription
	Signal transduction
	Signal transducer and activator of transcription 3
	DAXX
	Zipper-interacting protein kinase
	Krüppel-associated box-associated protein 1
	Y14
	PDZ and LIM domain 2
	Signal transducing adaptor protein-2
	Nuclear factor-κB
発行日	2015-11-26
出版者	Baishideng Publishing Group
収録物名	World journal of biological chemistry
巻(号)	6(4)
ページ	324-332
抄録	Signal transducers and activators of transcription (STATs) mediate essential signals for various biological processes, including immune responses, hematopoiesis, and neurogenesis. STAT3, for example, is involved in the pathogenesis of various human diseases, including cancers, autoimmune and inflammatory disorders. STAT3 activation is therefore tightly regulated at multiple levels to prevent these pathological conditions. A number of proteins have been reported to associate with STAT3 and regulate its activity. These STAT3-interacting proteins function to modulate STAT3-mediated signaling at various steps and mediate the crosstalk of STAT3 with other cellular signaling pathways. This article reviews the roles of novel STAT3 binding partners such as DAXX, zipper-interacting protein kinase, Krüppel-associated box-associated protein 1, Y14, PDZ and LIM domain 2 and signal transducing adaptor protein-2, in the regulation of STAT3-mediated signaling.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
権利情報	Creative Commons Attribution-NonCommercial 4.0 International
PISSN	1949-8454
関連情報	PMID 26629315
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.4331/wjbc.v6.i4.324