Morphological Characteristics of Genital Organ-Associated Lymphoid Tissue in the Vaginal Vestibule of Goats and Pigs

Chuluunbaatar, Tsolmon; Ichii, Osamu; Masum, Md. Abdul; Namba, Takashi; Kon, Yasuhiro

Morphological Characteristics of Genital Organ-Associated Lymphoid Tissue in the Vaginal Vestibule of Goats and Pigs

Chuluunbaatar, Tsolmon; Ichii, Osamu; Masum, Md. Abdul et al.

Veterinary Sciences, 2023, 10(1), 51

Permalink : https://hdl.handle.net/2115/88621

このアイテムのアクセス数:285件（2026-01-13 09:33 集計）

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https://doi.org/10.3390/vetsci10010051			1

論文情報

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アクセス権	metadata only access
URI	https://hdl.handle.net/2115/88621
タイトル	Morphological Characteristics of Genital Organ-Associated Lymphoid Tissue in the Vaginal Vestibule of Goats and Pigs
著者	Chuluunbaatar, Tsolmon ; Ichii, Osamu ; Masum, Md. Abdul ; Namba, Takashi ; Kon, Yasuhiro
著者名 Chuluunbaatar, Tsolmon
e-Rad_Researcher 60547769 著者名 Ichii, Osamu
著者名 Masum, Md. Abdul
著者名 Namba, Takashi
e-Rad_Researcher 10178402 著者名 Kon, Yasuhiro
言語	英語
キーワード	genital organ-associated lymphoid tissue
	mucosa-associated lymphoid tissue
	goat
	pig
	vaginal vestibule
	lymphatic nodule
	diffuse lymphoid tissue
発行日	2023-01-11
出版者	MDPI
収録物名	Veterinary Sciences
巻(号)	10(1)
ページ	51
抄録	Mucosa-associated lymphoid tissue (MALT) is a specialized form of peripheral lymphoid tissue (LT), which is found on mucosal surfaces exposed to the environment. However, morphological data of these tissues in farm animals are scarce. This study investigated the gross anatomical and histological features of genital organ-associated lymphoid tissues (GOALTs) in the vaginal vestibule (VV) of healthy, non-pregnant, adult goats and pigs. Their VVs were composed of stratified squamous, non-keratinized epithelium, and various-sized dark-blue hematoxylin-positive spots were observed in whole-mount specimens, which were diffusely distributed throughout the mucosal surfaces. These spots were histologically identified as LTs and consisted of lymphatic nodules (LNs) or diffuse lymphoid tissue (DLTs). Both LNs and DLTs contained B cells, T cells, macrophages, dendritic cells, plasma cells, and high endothelial venules. Only the numbers of B cells were significantly higher in both the LNs and DLTs of pigs compared to goats. Furthermore, the surface of the VV epithelium covering the LTs was partially disrupted with a large intercellular space containing abundant connective tissue fibers with numerous lymphocytes. In conclusion, GOALTs in the VV appear to be common local immunological barriers in both examined animals. This knowledge is crucial for understanding the structures and disorders of female reproductive organs in farm animals.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
EISSN	2306-7381
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.3390/vetsci10010051