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Oscillations and bifurcation structure of reaction-diffusion model for cell polarity formation

Kuwamura, Masataka; Izuhara, Hirofumi; Ei, Shin-ichiro

Journal of mathematical biology, 2022, 84(4), 22

Permalink : https://hdl.handle.net/2115/88700

このアイテムのアクセス数:250件（2026-01-22 21:56 集計）

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論文情報

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アクセス権
open access
URI
https://hdl.handle.net/2115/88700
タイトル
Oscillations and bifurcation structure of reaction-diffusion model for cell polarity formation
著者
Kuwamura, Masataka ; Izuhara, Hirofumi ; Ei, Shin-ichiro
e-Rad_Researcher
30270333
著者名
Kuwamura, Masataka
e-Rad_Researcher
50515096
著者名
Izuhara, Hirofumi
e-Rad_Researcher
30201362
著者名
Ei, Shin-ichiro
言語
英語
キーワード
Cell polarity oscillations
Reaction-diffusion system
Bistable nonlinearity
発行日
2022-02-25
出版者
Springer
収録物名
Journal of mathematical biology
巻(号)
84(4)
ページ
22
抄録
We investigate the oscillatory dynamics and bifurcation structure of a reaction-diffusion system with bistable nonlinearity and mass conservation, which was proposed by (Otsuji et al., PLoS Comp Biol 3:e108, 2007). The system is a useful model for understanding cell polarity formation. We show that this model exhibits four different spatiotemporal patterns including two types of oscillatory patterns, which can be regarded as cell polarity oscillations with the reversal and non-reversal of polarity, respectively. The trigger causing these patterns is a diffusion-driven (Turing-like) instability. Moreover, we investigate the effects of extracellular signals on the cell polarity oscillations.
資源タイプ
学術雑誌論文
出版タイプ
Accepted Manuscript
権利情報
This is a pre-print of an article published in Journal of mathematical biology. The final authenticated version is available online at: https://doi.org/10.1007/s00285-022-01723-5
PISSN
0303-6812
EISSN
1432-1416
関連情報 (isVersionOf)
出版社版DOI
https://doi.org/10.1007/s00285-022-01723-5