Association between Edinburgh Postnatal Depression Scale and Serum Levels of Ketone Bodies and Vitamin D, Thyroid Function, and Iron Metabolism

Noshiro, Kiwamu; Umazume, Takeshi; Inubashiri, Mayumi; Tamura, Megumi; Hosaka, Masayoshi; Watari, Hidemichi

Association between Edinburgh Postnatal Depression Scale and Serum Levels of Ketone Bodies and Vitamin D, Thyroid Function, and Iron Metabolism

Noshiro, Kiwamu; Umazume, Takeshi; Inubashiri, Mayumi et al.

Nutrients, 2023, 15(3), 768

Permalink : https://hdl.handle.net/2115/89267

このアイテムのアクセス数:266件（2026-01-17 19:11 集計）

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アクセス権	metadata only access
URI	https://hdl.handle.net/2115/89267
タイトル	Association between Edinburgh Postnatal Depression Scale and Serum Levels of Ketone Bodies and Vitamin D, Thyroid Function, and Iron Metabolism
著者	Noshiro, Kiwamu ; Umazume, Takeshi ; Inubashiri, Mayumi ; Tamura, Megumi ; Hosaka, Masayoshi ; Watari, Hidemichi
著者名 Noshiro, Kiwamu
e-Rad_Researcher 00807935 著者名 Umazume, Takeshi
著者名 Inubashiri, Mayumi
著者名 Tamura, Megumi
著者名 Hosaka, Masayoshi
e-Rad_Researcher 10344508 著者名 Watari, Hidemichi
言語	英語
キーワード	ketone body
	3-hydroxybutyric acid
	pregnancy
	postpartum depression
	Edinburgh Postnatal Depression Scale
発行日	2023-02
出版者	MDPI
収録物名	Nutrients
巻(号)	15(3)
ページ	768
抄録	Suicide due to postpartum depression is the most common perinatal-related death and is a social concern in Japan. Nutritional deficiencies during pregnancy may contribute to postpartum depression; therefore, we investigated the relationship between postpartum depression and nutritional status during pregnancy and postpartum. We focused specifically on ketone bodies because they are known to protect brain cells. The relationship between the Edinburgh Postnatal Depression Scale (EPDS) scores and the serum levels of ketone bodies and vitamin D, thyroid function, and iron metabolism was examined. Overall, 126 pregnant women were identified for the study, and 99 were eventually included in the analysis. We defined an EPDS score of >= 9 as being positive for postpartum depression, and serum ketone levels were found to be higher in the group with an EPDS score of >= 9 during the second trimester; however, there were no other significant findings. We may be able to predict postpartum depression from a pregnant woman's serum ketone levels in the second trimester. There was a positive correlation between the EPDS scores at 3 days and 1 month postpartum (r = 0.534, p < 0.001). EPDS scores assessed in the early postpartum period may be useful for the timely detection of postpartum depression.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.3390/nu15030768