Outcomes of laparoscopic total gastrectomy in elderly patients : a propensity score matching analysis

Ebihara, Yuma; Kurashima, Yo; Watanabe, Yusuke et al.

Langenbeck's archives of surgery, 2022, 407(4), 1461-1469

Permalink : https://hdl.handle.net/2115/89786

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論文情報

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アクセス権
open access
URI
https://hdl.handle.net/2115/89786
タイトル
Outcomes of laparoscopic total gastrectomy in elderly patients : a propensity score matching analysis
著者
Ebihara, Yuma ; Kurashima, Yo ; Watanabe, Yusuke ; Tanaka, Kimitaka ; Matsui, Aya ; Nakanishi, Yoshitsugu ; Asano, Toshimichi ; Noji, Takehiro ; Nakamura, Toru ; Murakami, Soichi ; Tsuchikawa, Takahiro ; Okamura, Keisuke ; Murakami, Yoshihiro ; Murakawa, Katsuhiko ; Nakamura, Fumitaka ; Morita, Takayuki ; Okushiba, Shunichi ; Shichinohe, Toshiaki ; Hirano, Satoshi
e-Rad_Researcher
50632981
著者名
Ebihara, Yuma
e-Rad_Researcher
40374350
著者名
Kurashima, Yo
著者名
Watanabe, Yusuke
e-Rad_Researcher
10758642
著者名
Tanaka, Kimitaka
e-Rad_Researcher
20894950
著者名
Matsui, Aya
著者名
Nakanishi, Yoshitsugu
著者名
Asano, Toshimichi
e-Rad_Researcher
10739296
著者名
Noji, Takehiro
著者名
Nakamura, Toru
著者名
Murakami, Soichi
e-Rad_Researcher
50507572
著者名
Tsuchikawa, Takahiro
著者名
Okamura, Keisuke
著者名
Murakami, Yoshihiro
著者名
Murakawa, Katsuhiko
著者名
Nakamura, Fumitaka
著者名
Morita, Takayuki
著者名
Okushiba, Shunichi
e-Rad_Researcher
70374353
著者名
Shichinohe, Toshiaki
e-Rad_Researcher
50322813
著者名
Hirano, Satoshi
言語
英語
キーワード
Laparoscopic total gastrectomy
Gastric cancer
Elderly patients
Multicenter retrospective study
発行日
2022-06-01
出版者
Springer
収録物名
Langenbeck's archives of surgery
巻(号)
407(4)
ページ
1461-1469
抄録
Purpose This study evaluated the short-term outcomes and prognosis after laparoscopic total gastrectomy (LTG) in elderly patients aged >= 80 years in a multicenter retrospective cohort study using propensity score matching. Methods We retrospectively enrolled 440 patients who underwent curative LTG for gastric cancer at six institutions between January 2004 and December 2018. Patients were categorized into an elderly patient group (EG; age >= 80 years) and non-elderly patient group (non-EG; age < 80 years). Patients were matched using the following propensity score covariates: sex, body mass index, American Society of Anesthesiologists physical status, extent of lymph node dissection, and Japanese Classification of Gastric Carcinoma stage. Short-term outcomes and prognoses were compared. Results We identified 37 propensity score-matched pairs. The median operative time was significantly shorter, and postoperative stay was longer in the EG. In terms of postoperative outcomes, the rates of all complications were comparable. The median follow-up period of the EG and non-EG was 11.5 (1-106.4) months and 35.7 (1-110.0) months, respectively; there were significant differences in 5-year overall survival between the two groups (EG, 58.5% vs. non-EG, 91.5%; P = 0.031). However, there were no significant differences in 5-year disease-specific survival (EG, 62.1% vs. non-EG, 91.5%; P = 0.068) or 5-year disease-free survival (EG, 52.9% vs. non-EG, 60.8%; P = 0.132). Conclusions LTG seems to be safe and feasible in elderly patients. LTG had a limited effect on morbidity, disease recurrence, and survival in elderly patients. Therefore, age should not prevent elderly patients from benefitting from LTG.
資源タイプ
学術雑誌論文
出版タイプ
Accepted Manuscript
権利情報
This is a post-peer-review, pre-copyedit version of an article published in Langenbeck's archives of surgery. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00423-022-02447-2
PISSN
1435-2443
関連情報 (isVersionOf)
出版社版DOI
https://doi.org/10.1007/s00423-022-02447-2