Impact of citrus fruit intake on the mental health of patients with chronic heart failure

Kakutani, Naoya; Yokota, Takashi; Fukushima, Arata et al.

Journal of cardiology, 2022, 79(6), 719-726

Permalink : https://hdl.handle.net/2115/89792

このアイテムのアクセス数:412件（2026-01-18 10:49 集計）

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J Cardiol 79(6) 719-726 pdf 2.18 MB 176
Graphical abstract (Citrus fruits) tiff 9.19 MB 117

論文情報

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アクセス権
open access
URI
https://hdl.handle.net/2115/89792
タイトル
Impact of citrus fruit intake on the mental health of patients with chronic heart failure
著者
Kakutani, Naoya ; Yokota, Takashi ; Fukushima, Arata ; Obata, Yoshikuni ; Ono, Taisuke ; Sota, Takeshi ; Kinugasa, Yoshiharu ; Takahashi, Masashige ; Matsuo, Hisashi ; Matsukawa, Ryuichi ; Yoshida, Ichiro ; Kakinoki, Shigeo ; Yonezawa, Kazuya ; Himura, Yoshihiro ; Yokota, Isao ; Yamamoto, Kazuhiro ; Tsuchihashi-Makaya, Miyuki ; Kinugawa, Shintaro
著者名
Kakutani, Naoya
e-Rad_Researcher
90374321
著者名
Yokota, Takashi
著者名
Fukushima, Arata
著者名
Obata, Yoshikuni
著者名
Ono, Taisuke
著者名
Sota, Takeshi
著者名
Kinugasa, Yoshiharu
著者名
Takahashi, Masashige
著者名
Matsuo, Hisashi
著者名
Matsukawa, Ryuichi
著者名
Yoshida, Ichiro
著者名
Kakinoki, Shigeo
著者名
Yonezawa, Kazuya
著者名
Himura, Yoshihiro
e-Rad_Researcher
20761414
著者名
Yokota, Isao
著者名
Yamamoto, Kazuhiro
著者名
Tsuchihashi-Makaya, Miyuki
著者名
Kinugawa, Shintaro
言語
英語
キーワード
Antioxidant
Chronic heart failure
Citrus fruits
Depression
Oxidative stress
Vitamin C
beta-carotene
beta-cryptoxanthin
発行日
2022-06
出版者
Elsevier
収録物名
Journal of cardiology
巻(号)
79(6)
ページ
719-726
抄録
Background: The full impact of the intake of citrus fruits on the risk of depression in individuals with chronic heart failure (HF) is unknown. Here, we examined the associations between the estimated habitual intakes of citrus fruits and depressive symptoms in patients with chronic HF. Methods: We enrolled 150 stable outpatients with chronic HF who had a history of worsening HF. To assess the patients' daily dietary patterns, we used a brief self-administered diet-history questionnaire to calculate the daily consumption of foods and nutrients. To assess the patients' mental state, we used a nine-item Patient Health Questionnaire (PHQ-9). Results: Twelve patients (8%) were identified as having moderate-to-severe depression (PHQ-9 score > 10). The patients with PHQ-9 > 10 had lower daily intakes of citrus fruits compared to those with no or mild depressive symptoms (PHQ-9 < 10). The daily intakes of various antioxidants, including vitamin C, beta- carotene, and beta-cryptoxanthin, all of which are abundant in citrus fruits, were reduced in the patients with PHQ-9 > 10, accompanied by higher serum levels of 8-isoprostane (an oxidative stress marker). A multivariate logistic regression analysis using forward selection showed that a lowered daily intake of citrus fruits was an independent predictor of the comorbidity of moderate-to-severe depression in patients with chronic HF, after adjustment for age, gender, and the hemoglobin value. Conclusions: A lower daily consumption of citrus fruits was associated with higher prevalence of depression in patients with chronic HF. Our findings support the hypothesis that a daily consumption of citrus fruits has a beneficial effect on the prevention and treatment of depression in chronic HF patients. (C)2021 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
資源タイプ
学術雑誌論文
出版タイプ
Accepted Manuscript
権利情報
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
権利情報
© 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
PISSN
0914-5087
関連情報 (isVersionOf)
出版社版DOI
https://doi.org/10.1016/j.jjcc.2021.12.004