Physicochemical functionality of chimeric isomaltomegalosaccharides with α-(1→4)-glucosidic segments of various lengths

Lang, Weeranuch; Kumagai, Yuya; Habu, Shinji; Sadahiro, Juri; Tagami, Takayoshi; Okuyama, Masayuki; Kitamura, Shinichi; Sakairi, Nobuo; Kimura, Atsuo

Physicochemical functionality of chimeric isomaltomegalosaccharides with α-(1→4)-glucosidic segments of various lengths

Lang, Weeranuch; Kumagai, Yuya; Habu, Shinji et al.

Carbohydrate Polymers, 2022, 291, 119562

Permalink : https://hdl.handle.net/2115/90331

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アクセス権	open access
URI	https://hdl.handle.net/2115/90331
タイトル	Physicochemical functionality of chimeric isomaltomegalosaccharides with α-(1→4)-glucosidic segments of various lengths
著者	Lang, Weeranuch ; Kumagai, Yuya ; Habu, Shinji ; Sadahiro, Juri ; Tagami, Takayoshi ; Okuyama, Masayuki ; Kitamura, Shinichi ; Sakairi, Nobuo ; Kimura, Atsuo
著者名 Lang, Weeranuch
著者名 Kumagai, Yuya
著者名 Habu, Shinji
著者名 Sadahiro, Juri
e-Rad_Researcher 70709849 著者名 Tagami, Takayoshi
e-Rad_Researcher 00344490 著者名 Okuyama, Masayuki
著者名 Kitamura, Shinichi
e-Rad_Researcher 60153863 著者名 Sakairi, Nobuo
e-Rad_Researcher 90186312 著者名 Kimura, Atsuo
言語	英語
キーワード	Dextran dextrinase
	Isomaltomegalosaccharide
	Chimeric structure
	Bifunctionality
	Quercetin flavonoid
	Water solubility enhancement
発行日	2022-09-01
出版者	Elsevier
収録物名	Carbohydrate Polymers
巻(号)	291
ページ	119562
抄録	Isomaltomegalosaccharide (IMS) is a long chimeric glucosaccharide composed of alpha-(1-+ 6)-and alpha-(1-+ 4)-linked segments at nonreducing and reducing ends, respectively; the hydrophilicity and hydrophobicity of these segments are expected to lead to bifunctionality. We enzymatically synthesized IMS with average degrees of polymerization (DPs) of 15.8, 19.3, and 23.5, where alpha-(1-+ 4)-segments had DPs of 3, 6, and 9, respectively. IMS exhibited considerably higher water solubility than maltodextrin because of the alpha-(1-+ 6)-segment and an identical resistance to thermal degradation as short dextran. Interaction of IMS with a fluorescent probe of 2-p- toluidinylnaphthalene-6-sulfonate demonstrated that IMS was more hydrophobic than maltodextrin, where the degree of hydrophobicity increased as DP of alpha-(1-+ 4)-segment increased (9 > 6 > 3). Fluorescent pyreneestimating polarity of IMS was found to be similar to that of methanol or 1-butanol. The bifunctional IMS enhanced the water solubility of quercetin-3-O-glucoside and quercetin: the solubilization of less-soluble bioactive substances is beneficial in carbohydrate industry.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
権利情報	© 2022. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
PISSN	0144-8617
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.carbpol.2022.119562