open access

https://hdl.handle.net/2115/91974

An Electron-Deficient Cp-E Iridium(III) Catalyst: Synthesis, Characterization, and Application to Ether-Directed C-H Amidation

英語

Iridium

2023-03-14

Wiley-Blackwell

Angewandte chemie-international edition

62(21)

e202301259

The synthesis, characterization, and catalytic performance of an iridium(III) catalyst with an electron-deficient cyclopentadienyl ligand ([(CpIrI2)-Ir-E](2)) are reported. The [(CpIrI2)-Ir-E](2) catalyst was synthesized by complexation of a precursor of the Cp-E ligand with [Ir(cod)OAc](2), followed by oxidation, desilylation, and removal of the COD ligand. The electron-deficient [(CpIrI2)-Ir-E](2) catalyst enabled C-H amidation reactions assisted by a weakly coordinating ether directing group. Experimental mechanistic studies and DFT calculations suggested that the high catalytic performance of [(CpIrI2)-Ir-E](2) is due to its electron-deficient nature, which accelerates both C-H activation and Ir-V-nitrenoid formation.

学術雑誌論文

Accepted Manuscript

This is the peer reviewed version of the following article: https://onlinelibrary.wiley.com/doi/10.1002/anie.202301259, which has been published in final form at https://doi.org/10.1002/anie.202301259. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.

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