Water-resistant antibacterial properties of a graphene oxide/cetylpyridinium chloride complex formed on medical gauze fibers

Kanemoto, Yukimi; Miyaji, Hirofumi; Nishida, Erika; Hamamoto, Asako; Sugaya, Tsutomu; Gohda, Syun; Ono, Hironobu

Water-resistant antibacterial properties of a graphene oxide/cetylpyridinium chloride complex formed on medical gauze fibers

Kanemoto, Yukimi; Miyaji, Hirofumi; Nishida, Erika et al.

Journal of oral biosciences, 2023, 65(2), 202-205

Permalink : https://hdl.handle.net/2115/92702

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アクセス権	open access
URI	https://hdl.handle.net/2115/92702
タイトル	Water-resistant antibacterial properties of a graphene oxide/cetylpyridinium chloride complex formed on medical gauze fibers
著者	Kanemoto, Yukimi ; Miyaji, Hirofumi ; Nishida, Erika ; Hamamoto, Asako ; Sugaya, Tsutomu ; Gohda, Syun ; Ono, Hironobu
e-Rad_Researcher 80972976 著者名 Kanemoto, Yukimi
e-Rad_Researcher 50372256 著者名 Miyaji, Hirofumi
e-Rad_Researcher 50779882 著者名 Nishida, Erika
著者名 Hamamoto, Asako
e-Rad_Researcher 10211301 著者名 Sugaya, Tsutomu
著者名 Gohda, Syun
著者名 Ono, Hironobu
言語	英語
キーワード	Actinomyces naeslundii
	Cationic surface active agent
	Escherichia coli
	Graphene oxide
	Medical gauze
発行日	2023-06
出版者	Elsevier
収録物名	Journal of oral biosciences
巻(号)	65(2)
ページ	202-205
抄録	Objectives: Graphene oxide (GO) is a nanocarbon material with a high aspect ratio (width:thickness) and abundant anionic functional groups on its surface. In this study, we attached GO to the surface of medical gauze fibers, constructed a complex with a cationic surface active agent (CSAA), and demonstrated that the treated gauze exhibits antibacterial activity even after rinsing with water.Methods: Medical gauze was immersed in GO dispersion (0.001%, 0.01%, and 0.1%), rinsed with water, dried, and subjected to the Raman spectroscopy analysis. Subsequently, the gauze treated with 0.001% GO dispersion was immersed in 0.1% cetylpyridinium chloride (CPC) solution, immediately rinsed with water, and dried. Untreated, GO-only, and CPC-only gauzes were prepared for comparison. Each gauze was placed in a culture well, seeded with Escherichia coli or Actinomyces naeslundii, and turbidity was measured after 24 h of incubation.Results: The Raman spectroscopy analysis of the gauze after immersion and rinsing showed a G band peak, indicating that GO remained on the surface of the gauze. The turbidity measurements indicated that GO/CPC-treated gauze (GO-treated and rinsed, followed by CPC-treatment and rinsing) significantly decreased turbidity compared to the other gauzes (P < 0.05), suggesting that the GO/CPC complex remained on the gauze fibers even after water rinsing and showed antibacterial activity.Conclusions: The GO/CPC complex imparts water-resistant antibacterial properties to gauze and has the potential to be widely used for the antimicrobial treatment of clothes.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
権利情報	©2023. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
PISSN	1349-0079
関連情報	PMID 36809828
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.job.2023.02.002