BODNs as biocompatible brominating reagents : visible-light photocatalytic tyrosine modification under physiologically favorable conditions

Yoshida, Rakuto; Hori, Yuichiro; Uraguchi, Daisuke et al.

Chemical communications, 2024, 85, 12381-12384

Permalink : https://hdl.handle.net/2115/96070

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アクセス権	open access
URI	https://hdl.handle.net/2115/96070
タイトル	BODNs as biocompatible brominating reagents : visible-light photocatalytic tyrosine modification under physiologically favorable conditions
著者	Yoshida, Rakuto ; Hori, Yuichiro ; Uraguchi, Daisuke ; Asano, Keisuke
著者名 Yoshida, Rakuto
著者名 Hori, Yuichiro
e-Rad_Researcher 70426328 著者名 Uraguchi, Daisuke
e-Rad_Researcher 90711771 著者名 Asano, Keisuke
言語	英語
発行日	2024-10-01
出版者	Royal Society of Chemistry
収録物名	Chemical communications
巻(号)	85
ページ	12381-12384
抄録	The photochemical reactivity of 1-bromo-2-oxo-1,2-dihydronaphthalene-1-carboxylates (BODNs) was demonstrated. They are inert in the dark under physiological conditions but become active as brominating reagents for tyrosine modification under visible light irradiation in the presence of a photocatalyst. The BODNs can be applied to protein labeling with bromo groups as sensitive mass tags. BODNs are inert in the dark under physiological conditions but become active as brominating reagents for tyrosine modification under visible light irradiation with a photocatalyst, leading to protein labeling with bromo groups as sensitive mass tags.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
PISSN	1359-7345
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1039/d4cc04171b