Accuracy verification of protoacoustic measurements in a heterogeneous phantom by an optical hydrophone

Chen, Ye; Kasamatsu, Koki; Kuriyama, Yasutoshi; Uesugi, Tomonori; Ishi, Yoshihiro; Murakami, Taichi; Hidani, Sena; Caulfield, Michael; Unlu, Mehmet Burcin; Rohringer, Wolfgang; Matsuura, Taeko

Accuracy verification of protoacoustic measurements in a heterogeneous phantom by an optical hydrophone

Chen, Ye; Kasamatsu, Koki; Kuriyama, Yasutoshi et al.

Medical physics, 2025, 52(3), 1893-1902

Permalink : https://hdl.handle.net/2115/97369

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アクセス権	open access
URI	https://hdl.handle.net/2115/97369
タイトル	Accuracy verification of protoacoustic measurements in a heterogeneous phantom by an optical hydrophone
著者	Chen, Ye ; Kasamatsu, Koki ; Kuriyama, Yasutoshi ; Uesugi, Tomonori ; Ishi, Yoshihiro ; Murakami, Taichi ; Hidani, Sena ; Caulfield, Michael ; Unlu, Mehmet Burcin ; Rohringer, Wolfgang ; Matsuura, Taeko
e-Rad_Researcher 20833073 著者名 Chen, Ye
著者名 Kasamatsu, Koki
著者名 Kuriyama, Yasutoshi
著者名 Uesugi, Tomonori
著者名 Ishi, Yoshihiro
著者名 Murakami, Taichi
著者名 Hidani, Sena
著者名 Caulfield, Michael
著者名 Unlu, Mehmet Burcin
著者名 Rohringer, Wolfgang
e-Rad_Researcher 90590266 著者名 Matsuura, Taeko
言語	英語
キーワード	optical hydrophone
	protoacoustics
	proton therapy
発行日	2025-03
出版者	John Wiley & Sons
収録物名	Medical physics
巻(号)	52(3)
ページ	1893-1902
抄録	Background : Protoacoustics has emerged as a promising real-time range measurement method for proton therapy. Optical hydrophones (OHs) are considered suitable to detect protoacoustic waves owing to their ultracompact size and high sensitivity. In our previous research, we demonstrated that the time-of-arrival (TOA) measured by an OH showed good agreement with the simulated ground truth in a homogeneous medium.
	Purpose : The purpose of the study was to experimentally evaluate the accuracy of the TOA and compression peak pressures detected by the OH. Protoacoustic waves that undergo the typical distortions occurring in the human body were investigated. In such cases, the use of small detectors such as OHs is desirable to minimize the effects of detector size and directivity.
	Methods : A 100-MeV proton pencil beam emitted from a fixed-field alternating gradient accelerator was irradiated onto a homogeneous water phantom and a water phantom with a half- or full-sized silicone plate downstream of the Bragg peak (BP) or a bone plate that covered half of the beam cross-section in the beam path. The OH was shifted 70 mm laterally across the beam axis downstream of the BP to measure the protoacoustic waves. The k-WAVE acoustic wave transport simulation was employed as the ground truth. The TOA and the first compression peak pressures were compared between the simulation and experiment.
	Results : The TOA deviation against the ground truth was primarily attributed to alignment errors of the measurement devices and phantoms, with deviations of < 1 mm. The peak pressure distribution closely resembled the ground truth, with FWHM differences of 0.0%–3.0% for the tested geometries.
	Conclusion : The OH was able to determine the TOA and peak pressures with sufficient accuracy in heterogeneous phantoms, even without considering the effect of the size of the detector or directivity on the measurements.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	This is the peer reviewed version of the following article: Chen Y, Kasamatsu K, Kuriyama Y, et al. Accuracy verification of protoacoustic measurements in a heterogeneous phantom by an optical hydrophone. Med Phys. 2025; 52: 1893–1902, which has been published in final form at https://doi.org/10.1002/mp.17575. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
PISSN	0094-2405
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1002/mp.17575