open access

https://hdl.handle.net/2115/97894

Direct Site-Selective Deoxygenation of Benzylalcohol Derivatives

英語

transesterifications

2025-06-19

Wiley-Blackwell

Advanced synthesis & catalysis

367(14)

e9590

A simple yet efficient method is presented for direct and site-selective deoxygenation of benzyl alcohol derivatives, including polyols, without requiring preactivation. This reaction system, consisting of Hantzsch ester, Cs2CO3, and a photocatalyst under photoirradiation, enables direct and site-selective deoxygenation. Mechanistic studies reveal that in situ reversible acylative activation of hydroxy groups plays a pivotal role in achieving unique selectivity. This approach offers a general and practical strategy for the selective transformation of polyols.

学術雑誌論文

Accepted Manuscript

This is the peer reviewed version of the following article: https://advanced.onlinelibrary.wiley.com/doi/10.1002/adsc.9590, which has been published in final form at https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/adsc.9590. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.

1615-4150