Predictors and Proarrhythmic Consequences of Inappropriate Implantable Cardioverter-Defibrillator Therapy

Tenma, Taro; Yokoshiki, Hisashi; Mizukami, Kazuya; Mitsuyama, Hirofumi; Watanabe, Masaya; Sasaki, Ryo; Maeno, Motoki; Matsui, Yoshiro; Tsutsui, Hiroyuki

Predictors and Proarrhythmic Consequences of Inappropriate Implantable Cardioverter-Defibrillator Therapy

Tenma, Taro; Yokoshiki, Hisashi; Mizukami, Kazuya et al.

Circulation Journal, 2015, 79(9), 1920-1927

Permalink : https://hdl.handle.net/2115/71892

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論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/71892
タイトル	Predictors and Proarrhythmic Consequences of Inappropriate Implantable Cardioverter-Defibrillator Therapy
著者	Tenma, Taro ; Yokoshiki, Hisashi ; Mizukami, Kazuya ; Mitsuyama, Hirofumi ; Watanabe, Masaya ; Sasaki, Ryo ; Maeno, Motoki ; Matsui, Yoshiro ; Tsutsui, Hiroyuki
著者名 Tenma, Taro
e-Rad_Researcher 40360911 著者名 Yokoshiki, Hisashi
著者名 Mizukami, Kazuya
著者名 Mitsuyama, Hirofumi
著者名 Watanabe, Masaya
著者名 Sasaki, Ryo
著者名 Maeno, Motoki
e-Rad_Researcher 90219379 著者名 Matsui, Yoshiro
e-Rad_Researcher 70264017 著者名 Tsutsui, Hiroyuki
言語	英語
キーワード	Antitachycardia pacing
	Implantable cardioverter-defibrillator
	Inappropriate shock
	Paroxysmal atrial fibrillation
	Proarrhythmia
発行日	2015-08-25
出版者	The Japanese Circulation Society
収録物名	Circulation Journal
巻(号)	79(9)
ページ	1920-1927
抄録	Background: Despite the benefits of implantable cardioverter-defibrillator (ICD) therapy, inappropriate shocks can lead to multiple adverse effects. The aim of this study was to clarify the predictors of inappropriate ICD shocks and their proarrhythmic consequences. Methods and Results: We retrospectively studied 316 consecutive patients who underwent ICD implantation from December 2000 to December 2011. Of them, 70 (22%) experienced inappropriate ICD shocks without proarrhythmia requiring some intervention; 2 patients (0.6%) had proarrhythmic inappropriate ICD therapy by antitachycardia pacing (ATP), thereby calculated to be 0.18% of patients per year. However, they did not have syncope from this inappropriate ATP. Multivariate analysis identified younger age (≤56 years: hazard ratio [HR] 1.68, 95% confidence interval [CI] 1.02-2.77, P=0.043), paroxysmal atrial fibrillation (HR 3.00, 95% CI 1.64-5.31, P=0.0002), stroke (HR 2.23, 95% CI 1.11-4.47, P=0.024), and no diuretic use (HR 1.72, 95% CI 1.03-2.93, P=0.039) as independent predictors of the occurrence of inappropriate ICD shocks. Conclusions: Young age, paroxysmal atrial fibrillation, stroke, and no use of diuretics were independently associated with inappropriate ICD shocks. Proarrhythmic inappropriate ICD therapy was observed with an annual incidence of 0.18% by ATP.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
PISSN	1346-9843
EISSN	1347-4820
関連情報	PMID 26104029
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.1253/circj.CJ-15-0306