+ More

Copper-Catalyzed Enantioselective Coupling between Allylboronates and Phosphates Using a Phenol-Carbene Chiral Ligand: Asymmetric Synthesis of Chiral Branched 1,5-Dienes

Yasuda, Yuto; Ohmiya, Hirohisa; Sawamura, Masaya

Synthesis-stuttgart, 2018, 50(11), 2235-2246

Permalink : https://hdl.handle.net/2115/74534

このアイテムのアクセス数:652件（2026-10-17 08:09 集計）

閲覧可能ファイル 

ファイル フォーマット サイズ 閲覧回数 説明
Synthesis_revision.10 pdf 845 KB 792

論文情報

ファイル出力 EndNote Basic出力 Mendeley出力

アクセス権
open access
URI
https://hdl.handle.net/2115/74534
タイトル
Copper-Catalyzed Enantioselective Coupling between Allylboronates and Phosphates Using a Phenol-Carbene Chiral Ligand: Asymmetric Synthesis of Chiral Branched 1,5-Dienes
著者
Yasuda, Yuto ; Ohmiya, Hirohisa ; Sawamura, Masaya
著者名
Yasuda, Yuto
e-Rad_Researcher
40508876
著者名
Ohmiya, Hirohisa
e-Rad_Researcher
40202105
著者名
Sawamura, Masaya
言語
英語
キーワード
asymmetric catalysis
allylic substitution
synthetic methods copper catalysis
organoboron compounds
発行日
2018-06
出版者
Georg Thieme Verlag
収録物名
Synthesis-stuttgart
巻(号)
50(11)
ページ
2235-2246
抄録
Details of the Cu-catalyzed enantioselective allyl-allyl coupling reaction between allylboronates and (Z)-allylic phosphates using a new chiral N-heterocyclic carbene (NHC) ligand containing a phenolic hydroxy group are presented. The copper catalysis delivers enantioenriched chiral 1,5-dienes with a tertiary stereogenic center. Compatibility with various functional groups and the use of earth-abundant and relatively low-toxicity copper as a metal are attractive features of this protocol. The utility of the chiral phenol-NHC ligand for enantioselective copper catalysis with organoboron compounds is demonstrated and enantiodiscrimination models are discussed.
資源タイプ
学術雑誌論文
出版タイプ
Accepted Manuscript
権利情報
(c)2018 Georg Thieme Verlag KG
PISSN
0039-7881
関連情報 (isVersionOf)
出版社版DOI
https://doi.org/10.1055/s-0036-1591548