H13 influenza viruses in wild birds have undergone genetic and antigenic diversification in nature

Wang, Zu-Jyun; Kikutani, Yuto; Lam Thanh Nguyen; Hiono, Takahiro; Matsuno, Keita; Okamatsu, Masatoshi; Krauss, Scott; Webby, Richard; Lee, Youn-Jeong; Kida, Hiroshi; Sakoda, Yoshihiro

H13 influenza viruses in wild birds have undergone genetic and antigenic diversification in nature

Wang, Zu-Jyun; Kikutani, Yuto; Lam Thanh Nguyen et al.

Virus Genes, 2018, 54(4), 543-549

Permalink : https://hdl.handle.net/2115/75096

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論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/75096
タイトル	H13 influenza viruses in wild birds have undergone genetic and antigenic diversification in nature
著者	Wang, Zu-Jyun ; Kikutani, Yuto ; Lam Thanh Nguyen ; Hiono, Takahiro ; Matsuno, Keita ; Okamatsu, Masatoshi ; Krauss, Scott ; Webby, Richard ; Lee, Youn-Jeong ; Kida, Hiroshi ; Sakoda, Yoshihiro
著者名 Wang, Zu-Jyun
著者名 Kikutani, Yuto
著者名 Lam Thanh Nguyen
e-Rad_Researcher 00775819 著者名 Hiono, Takahiro
e-Rad_Researcher 40753306 著者名 Matsuno, Keita
e-Rad_Researcher 00507163 著者名 Okamatsu, Masatoshi
著者名 Krauss, Scott
著者名 Webby, Richard
著者名 Lee, Youn-Jeong
e-Rad_Researcher 10109506 著者名 Kida, Hiroshi
e-Rad_Researcher 40333637 著者名 Sakoda, Yoshihiro
言語	英語
キーワード	Avian influenza
	H13 subtype
	Antigenicity
	Genetics
発行日	2018-08
出版者	Springer
収録物名	Virus Genes
巻(号)	54(4)
ページ	543-549
抄録	Among 16 haemagglutinin (HA) subtypes of avian influenza viruses (AIVs), H13 AIVs have rarely been isolated in wild waterfowl. H13 AIVs cause asymptomatic infection and are maintained mainly in gull and tern populations; however, the recorded antigenic information relating to the viruses has been limited. In this study, 2 H13 AIVs, A/duck/Hokkaido/W345/2012 (H13N2) and A/duck/Hokkaido/WZ68/2012 (H13N2), isolated from the same area in the same year in our surveillance, were genetically and antigenically analyzed with 10 representative H13 strains including a prototype strain, A/gull/Maryland/704/1977 (H13N6). The HA genes of H13 AIVs were phylogenetically divided into 3 groups (I, II, and III). A/duck/Hokkaido/W345/2012 (H13N2) was genetically classified into Group III. This virus was distinct from a prototype strain, A/gull/Maryland/704/1977 (H13N6), and the virus, A/duck/Hokkaido/WZ68/2012 (H13N2), both belonging to Group I. Antigenic analysis indicated that the viruses of Group I were antigenically closely related to those of Group II, but distinct from those of Group III, including A/duck/Hokkaido/W345/2012 (H13N2). In summary, our study indicates that H13 AIVs have undergone antigenic diversification in nature.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	This is a post-peer-review, pre-copyedit version of an article published in Virus Genes. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11262-018-1573-0
PISSN	0920-8569
EISSN	1572-994X
NCID	AA10681748
関連情報	PMID 29796944
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1007/s11262-018-1573-0