Rose bengal-decorated rice husk-derived silica nanoparticles enhanced singlet oxygen generation for antimicrobial photodynamic inactivation

Mori, Nanase; Kawasaki, Hideya; Nishida, Erika et al.

Journal of Materials Science, 2023, 58(6), 2801-2813

Permalink : https://hdl.handle.net/2115/92681

このアイテムのアクセス数:194件（2026-08-17 11:38 集計）

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アクセス権
open access
URI
https://hdl.handle.net/2115/92681
タイトル
Rose bengal-decorated rice husk-derived silica nanoparticles enhanced singlet oxygen generation for antimicrobial photodynamic inactivation
著者
Mori, Nanase ; Kawasaki, Hideya ; Nishida, Erika ; Kanemoto, Yukimi ; Miyaji, Hirofumi ; Umeda, Junko ; Kondoh, Katsuyoshi
著者名
Mori, Nanase
e-Rad_Researcher
50322285
著者名
Kawasaki, Hideya
e-Rad_Researcher
50779882
著者名
Nishida, Erika
e-Rad_Researcher
80972976
著者名
Kanemoto, Yukimi
e-Rad_Researcher
50372256
著者名
Miyaji, Hirofumi
e-Rad_Researcher
50345162
著者名
Umeda, Junko
e-Rad_Researcher
50345138
著者名
Kondoh, Katsuyoshi
言語
英語
キーワード
rice husk
silica
rose bengal
photosensitizer
singlet oxygen
photodynamic therapy
発行日
2023-01-25
出版者
Springer
収録物名
Journal of Materials Science
巻(号)
58(6)
ページ
2801-2813
抄録
Rice husks (RHs) are well known for their high silica content, and the RH-derived silica nanoparticles (RH NPs) are amorphous and biocompatible; therefore, they are suitable raw materials for biomedical applications. In this study, rose bengal-impregnated rice husk nanoparticles (RB-RH NPs) were prepared for their potential photosensitization and 1O2 generation as antimicrobial photodynamic inactivation. RB is a halogen-xanthene type's PS showing high singlet oxygen efficiency, and the superior photophysical properties are desirable for RB in the antimicrobial photodynamic inactivation of bacteria. To enhance the binding of anionic RB to RH NPs, we conducted cationization for the RH NPs using polyethyleneimine (PEI). The control of the RB adsorption state on cationic PEI-modified RH NPs was essential for RB RH-NP photosensitizers to obtain efficient 1O2 generation. Minimizing RB aggregation allowed highly efficient 1O2 production from RB-RH NPs at the molar ratio of RB with the PEI, XRB/PEI. =0.1. The RB-RH NPs have significant antimicrobial activity against S. mutants compared to free RB after white light irradiation. The RB-RH NP-based antimicrobial photodynamic inactivation can be employed effectively in treating S. mutants for dental applications.
資源タイプ
学術雑誌論文
出版タイプ
Accepted Manuscript
権利情報
This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s10853-023-08194-z
PISSN
0022-2461
関連情報
PMID
36713647
関連情報 (isVersionOf)
出版社版DOI
https://doi.org/10.1007/s10853-023-08194-z