A case of uterine tumor resembling ovarian sex cord tumor with prominent myxoid features

Ise, Koki; Tanei, Zen-ichi; Oda, Yoshitaka; Tanikawa, Satoshi; Sugino, Hirokazu; Ishida, Yusuke; Tsuda, Masumi; Gotoda, Yuko; Nishiwaki, Kunihiko; Yanai, Hiroyuki; Hasegawa, Tadashi; Nagashima, Kazuo; Tanaka, Shinya

A case of uterine tumor resembling ovarian sex cord tumor with prominent myxoid features

Ise, Koki; Tanei, Zen-ichi; Oda, Yoshitaka et al.

International Journal of Gynecological Pathology, 2024, 43(1), 41-46

Permalink : https://hdl.handle.net/2115/94204

このアイテムのアクセス数:206件（2026-08-09 11:10 集計）

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UTROSCT case report_revise	pdf	1.79 MB	135
UTROSCT case report_revise_supplementary table	docx	49.7 KB	39

論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/94204
タイトル	A case of uterine tumor resembling ovarian sex cord tumor with prominent myxoid features
著者	Ise, Koki ; Tanei, Zen-ichi ; Oda, Yoshitaka ; Tanikawa, Satoshi ; Sugino, Hirokazu ; Ishida, Yusuke ; Tsuda, Masumi ; Gotoda, Yuko ; Nishiwaki, Kunihiko ; Yanai, Hiroyuki ; Hasegawa, Tadashi ; Nagashima, Kazuo ; Tanaka, Shinya
著者名 Ise, Koki
e-Rad_Researcher 90757650 著者名 Tanei, Zen-ichi
著者名 Oda, Yoshitaka
著者名 Tanikawa, Satoshi
著者名 Sugino, Hirokazu
著者名 Ishida, Yusuke
著者名 Tsuda, Masumi
著者名 Gotoda, Yuko
著者名 Nishiwaki, Kunihiko
著者名 Yanai, Hiroyuki
著者名 Hasegawa, Tadashi
著者名 Nagashima, Kazuo
e-Rad_Researcher 70261287 著者名 Tanaka, Shinya
言語	英語
発行日	2024-01
出版者	Lippincott Williams & Wilkins (LWW)
収録物名	International Journal of Gynecological Pathology
巻(号)	43(1)
ページ	41-46
抄録	Uterine tumor resembling ovarian sex cord tumor (UTROSCT) is a rare tumor with low malignant potential that commonly occurs in middle age. Although more than 100 cases have been reported to date, myxoid morphology is not well documented. Here, we present a 75-yr-old woman with abnormal vaginal bleeding, with an 8-cm mass in the uterine corpus detected by irregular, high-intensity signaling on T2-weighted imaging. The uterine mass had a glistening mucinous appearance on gross examination. Microscopically, most of the tumor cells were floating in the myxoid stroma. The tumor cells formed clusters or nests with abundant cytoplasm, while some exhibited trabecular or rhabdoid appearances. Immunohistochemically, tumor cells were positive for pancytokeratin (AE1/AE3), α-smooth muscle actin, CD10, progesterone receptor, and some sex cord markers such as calretinin, inhibin, CD56, steroidogenic factor-1. Electron microscopy demonstrated epithelial and sex cord differentiation. This tumor was negative for JAZF1–JJAZ1 fusion gene that is frequently found in low-grade endometrial stromal sarcoma. Fusion genes related to UTROSCT, including NCOA2/3, were not detected by reverse transcription polymerase chain reaction. The present case suggests that UTROSCT should be included in the differential diagnosis of myxoid uterine tumors.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	This is a non-final version of an article published in final form in Ise, Koki M.D.; Tanei, Zen-ichi M.D., Ph.D.; Oda, Yoshitaka M.D., Ph.D.; Tanikawa, Satoshi M.D., Ph.D.; Sugino, Hirokazu M.D., Ph.D.; Ishida, Yusuke M.D., Ph.D.; Tsuda, Masumi Ph.D; Gotoda, Yuko M.D., Ph.D.; Nishiwaki, Kunihiko M.D., Ph.D.; Yanai, Hiroyuki M.D., Ph.D.; Hasegawa, Tadashi M.D., Ph.D.; Nagashima, Kazuo M.D., Ph.D.; Tanaka, Shinya M.D., Ph.D.. A Case of Uterine Tumor Resembling Ovarian Sex Cord Tumor With Prominent Myxoid Features. International Journal of Gynecological Pathology 43(1):p 41-46, January 2024. \| DOI: 10.1097/PGP.0000000000000949.
PISSN	0277-1691
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1097/PGP.0000000000000949