Changes in cerebral hemodynamics during pediatric cardiac surgery with cardiopulmonary bypass for congenital heart disease

Takeda, Yoshifumi; Hoshino, Koji; Yamamoto, Masataka; Morimoto, Yuji

Changes in cerebral hemodynamics during pediatric cardiac surgery with cardiopulmonary bypass for congenital heart disease

Takeda, Yoshifumi; Hoshino, Koji; Yamamoto, Masataka et al.

Pediatric cardiology, 2024, 47(1), 74-83

Permalink : https://hdl.handle.net/2115/97332

このアイテムのアクセス数:41件（2026-07-12 15:11 集計）

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論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/97332
タイトル	Changes in cerebral hemodynamics during pediatric cardiac surgery with cardiopulmonary bypass for congenital heart disease
著者	Takeda, Yoshifumi ; Hoshino, Koji ; Yamamoto, Masataka ; Morimoto, Yuji
著者名 Takeda, Yoshifumi
e-Rad_Researcher 40802434 著者名 Hoshino, Koji
著者名 Yamamoto, Masataka
e-Rad_Researcher 00250457 著者名 Morimoto, Yuji
言語	英語
キーワード	Pediatric cardiac surgery
	Congenital heart disease
	Cardiopulmonary bypass
	Transcranial doppler ultrasonography
	Cerebral oxygen saturation
	Near-infrared spectroscopy
発行日	2024-12-11
出版者	Springer
収録物名	Pediatric cardiology
巻(号)	47(1)
ページ	74-83
抄録	During pediatric cardiac surgery with cardiopulmonary bypass (CPB) for congenital heart disease, systemic hemodynamics dramatically change, which also causes changes in the cerebral hemodynamics. One of the representative methods in bedside monitoring for the estimation of cerebral hemodynamics during pediatric cardiac surgery is transcranial Doppler ultrasonography (TCD). However, there seem to be few reports on the changes in TCD findings in such operations, especially in cyanotic children. Accordingly, we examined the changes in TCD indices during these procedures in cyanotic children as well as non-cyanotic children. In the post hoc analysis of a previous prospective observational study, TCD indices of the middle cerebral artery at the start and end of surgery in patients aged 6 years or less were compared. The cerebral oxygenation (rSO2) values were also compared. For this study, 47 cyanotic children and 49 non-cyanotic children were evaluated. At the end of surgery, cerebral blood flow velocities decreased and cerebrovascular resistance increased significantly compared to the start of surgery in both the cyanotic and non-cyanotic patients. This finding was almost constant regardless of age differences, although cerebral blood flow velocities and the rSO2 increased until around 20 months after birth. The rSO2 values did not change between the start and end of surgery. Thus, the changes in cerebral hemodynamics during pediatric surgery with CPB in cyanotic children were not so different from those in non-cyanotic children. The significance of monitoring of cerebral hemodynamics by TCD and rSO2 should be evaluated further.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00246-024-03727-y
PISSN	0172-0643
EISSN	1432-1971
関連情報	PMID 39661152
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1007/s00246-024-03727-y