Japanese Journal of Veterinary Research;Volume 2, Number 3

FONT SIZE:  S M L

THERAPEUTIC TREATMENTS IN EQUINE INFECTIOUS ANEMIA IV. : THE USE OF NITROMIN AND CHLOROMYCETIN FOR ARTIFICIALLY INOCULATED INFECTIOUS ANEMIA

NAKAMURA, Ryoichi;SAKAI, Tamotsu;SONODA, Mitsuo;KOIKE, Toshio;KAWATA, Keiichiro;TOO, Kimehiko

Permalink : http://hdl.handle.net/2115/1658
JaLCDOI : 10.14943/jjvr.2.3.101

Abstract

Therapeutic experiments in artificial equine infectious anemia with nitromin and chloromycetin were conducted. Comparisons were made with the findings of previous experiments performed in cases of natural chronic infectious anemia. The results thus obtained may be summarized as follows. 1. Nitromin has a serious toxity and aggravates the diseases. Especially, aggravation of cardiac disturbances are remarkable. 2. Blood cells, especially leucocytes, were decreased in numbers in accordance with repetition of the nitromin injection. 3. One or 3 days after treatments, in experimental horses Nos. 2 and 3,typical fever attacks of infectious anemia were found definitely. In autopsy findings, they were diagnosed as chronic infectious anemia cases. 4. In animal No. 1,siderocytes disappeared from the 3rd day of nitromin injection, but in the other 2 cases they were found usually. 5. While No. 2 showed gradual decrease in γ-globulin and glucose, other 2 cases presented no marked variations in biochemical findings. 6. Characteristic facts found in the present experiment were the disappearances of siderocytes in No. 1 and no indications of infectious anemia in its autopsy findings. However, it is impossible to believe that it could recover even had it not died suddenly. 7. In comparison with artificial and natural infectious anemia, except for No. 1,no differences were found in the therapeutic observations. As far as shown by above described data, it was indicated that these are no effective agents against the equine infectious anemia.

FULL TEXT:PDF