Japanese Journal of Veterinary Research;Volume 2, Number 4

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SOME OBSERVATIONS ON THE NON-SPECIFICALLY ENHANCED RESISTANCE OF MICE AGAINST INTRAPERITONEAL INFECTION WITH SALMONELLA ABORTUS-EQUI

SATO, Gihei;HIRATO, Katsushichi

Permalink : http://hdl.handle.net/2115/1665
JaLCDOI : 10.14943/jjvr.2.4.177

Abstract

Mice immunized intraperitoneally with killed vaccine of heterologous bacteria show an enhanced resistance to an intraperitoneal infection with S. abortus-equi 1 or 2 days after vaccination and sustain it for a period extending to 10 days. This non-specifically enhanced resistance is inferior to the resistance observed in specific immunization. However, in case of injecting a large dose of heterologous vaccine, non-specific rise in resistance sometimes becomes considerably high and lasts for 3 weeks.

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