Japanese Journal of Veterinary Research;Volume 18, Number 1

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BURSA OF FABRICIUS CONTAINING VIRUS-LIKE PARTICLES AN ELECTRON MICROSCOPIC OBSERVATION

SUGIMURA, Makoto;YAMADA, Junzo

Permalink : http://hdl.handle.net/2115/1943
JaLCDOI : 10.14943/jjvr.18.1.31

Abstract

A bursa of Fabricius containing numerous virus-like particles was examined. The structures and cells of the bursa seemed to be normal histologically, though the bursa was larger in size for the age of the chicken and under the electron microscope was seen to contain virus-like particles. The particles, about 800Å in size, were mainly found in the medulla of lymphoid follicles and were composed of a central dense nucleoid, surrounded by an envelope. Macrophages, which appeared to be epithelial in origin, in the medulla showed cytoplasmic inclusions or viroplasts and the budding of the plasma membrane. Thus, a similarity between the particles and the avian leukosis tumor virus, and the site of virus replication in the bursa have been discussed.

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