Japanese Journal of Veterinary Research;Volume 19, Number 3

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A CASE OF MEGALOBLASTIC ANEMIA IN THE GIBBON (HYLOBATES FOOLOCK)

MAEDE, Yoshimitsu;NIGI, Hideo

Permalink : http://hdl.handle.net/2115/1982
JaLCDOI : 10.14943/jjvr.19.3.81

Abstract

An adult female gibbon kept in a zoo for six years was affected with a disease showing diarrhea and anemia. Blood examinations revealed that she was diseased by the macrocytic megaloblastic anemia associated with a marked left shift in neutrophils. Nuclei of the neutrophils were large and bizarre, and Dohle bodies and toxic granules were observed in the cytoplasm. By the treatment with vitamin B_<12> injection for two days, the megaloblasts in peripheral blood disappeared and instead normoblasts increased. Autopsy findings showed no significant gross changes, however histopathologically, focal edematous induration in the liver and subacute catarrhal enterocolitis were markedly noticed.

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