Japanese Journal of Veterinary Research;Volume 30, Number 3-4

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PRODUCTION OF NEONATAL HEMOLYTIC DISEASE IN NEWBORN PIGS BY ORAL ADMINISTRATION OF ANTI-PORCINE ERYTHROCYTE OVINE SERUM

KAGOTA, Katsumoto;ABE, Noboru;TOKORO, Kazunobu

Permalink : http://hdl.handle.net/2115/2266
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Abstract

The minimum time of separating piglets from their mothers in order to prevent hemolytic disease in newborn pigs was investigated by examining the red blood cell count, packed blood cell volume, blood hemoglobin concentration and erythrocyte osmotic fragility of naturally suckled piglets which had been given anti-porcine erythrocyte ovine serum orally at different times after birth. The erythrocyte osmotic fragility test proved to be the most effective test to detect the hemolytic condition. Decrease in erythrocyte resistance was observed only in the piglets given the serum within 18 hours of life. From this result, it was recommended that piglets should be fostered by a non-sensitized sow other than their mother for 24 hours after birth to prevent the occurrence of neonatal hemolytic disease.

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