Japanese Journal of Veterinary Research;Volume 68 Number 4

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Characterization of canine hemangiosarcoma by 18F-Fluorodeoxyglucose Positron Emission Tomography

Chaudhary, Preeti Kumari;Kim, Sanggu;Yun, Taesik;Kang, Byeong-Teck;Kim, Soochong

Permalink : http://hdl.handle.net/2115/79939
JaLCDOI : 10.14943/jjvr.68.4.257
KEYWORDS : FDG-PET/CT;hemangiosarcoma;immunohistochemistry

Abstract

Our objective was to characterize the use of 18F-fluorodeoxyglucose (FDG)-PET/CT in the diagnosis of primary splenic hemangiosarcoma in combination with histopathology and immunohistochemistry. A 7-year-old castrated male mixed breed dog weighing 6 kg was presented with the complain of recurring pruritus, ulceration, and alopecia. X-ray and ultrasonography confirmed the splenic nodule of 0.5 cm in the abdominal cavity. Further FDG-PET/CT staging showed a hypermetabolic splenic mass with increased glucose uptake with SUVmax= 10.69 and SUVaverage= 5.172 with no distant metastases. Histopathology was consistent with splenic hemangiosarcoma. Tumor cells were strongly positive for CD31, a strong marker of cells with endothelial-origin. Thus, we report the first case that describes the utility of FDG-PET/CT in diagnosis of canine primary splenic hemangiosarcoma.

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