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RECOVERY OF INTENTIONAL DYNAMIC BALANCE FUNCTION AFTER INTRAVENOUS SEDATION WITH MIDAZOLAM IN YOUNG AND ELDERLY SUBJECTS
| Title: | RECOVERY OF INTENTIONAL DYNAMIC BALANCE FUNCTION AFTER INTRAVENOUS SEDATION WITH MIDAZOLAM IN YOUNG AND ELDERLY SUBJECTS |
| Authors: | Fujisawa, Toshiaki Browse this author →KAKEN DB | | Takuma, Shigeru Browse this author | | Koseki, Hiroyo Browse this author | | Kimura, Kunie Browse this author | | Fukushima, Kazuaki Browse this author |
| Keywords: | CONSCIOUS SEDATION | | MIDAZOLAM | | AGED | | RECOVERY OF FUNCTION | | MUSCULOSKELETAL EQUILIBRIUM | | intentional dynamic balance |
| Issue Date: | 1-Mar-2006 |
| Publisher: | Cambridge University Press |
| Journal Title: | European Journal of Anaesthesiology |
| Volume: | 23 |
| Start Page: | 422 |
| End Page: | 425 |
| Publisher DOI: | 10.1017/S0265021506000019 |
| PMID: | 16507179 |
| Abstract: | Background and objective: Computerized dynamic posturography using an intentional postural sway task can be used to assess body-leaning ability and postural control ability to prevent falls. Falls are the leading cause of morbidity and mortality for the elderly. The purpose of the present study was to evaluate the recovery of intentional dynamic balance function after intravenous sedation with midazolam in elderly subjects in comparison with that in young subjects.
Methods: Midazolam was administered in small, divided doses over 4 to 5 minutes until the Wilson sedation score reached 3 in 20 young and 18 elderly male volunteers. A dynamic limits of stability test, in which subjects leaned their body intentionally as indicated by a cursor moving on a computer screen, was performed before (baseline) and 50, 70, 90, 110, and 130 minutes after administration of midazolam.
Results: The changes from baseline values of path sway and movement time 50 minutes after the administration of midazolam in elderly subjects (106.8101.0 %, 4.63.0 seconds; meanSD) were significantly greater than those (32.987.2%, 1.92.8 seconds) in young subjects (p=0.024, p=0.008), respectively.
Conclusions: The elderly show slower recovery of the intentional dynamic balance function than do young adults after intravenous sedation with midazolam. |
| Rights: | 2006 European Journal of Anaethesiology |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/10093 |
| Appears in Collections: | 歯学院・歯学研究院 (Graduate School of Dental Medicine / Faculty of Dental Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 藤澤 俊明
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