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Normal and high-normal blood pressures, but not body mass index, are risk factors for the subsequent occurrence of both preeclampsia and gestational hypertension : A retrospective cohort study

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Title: Normal and high-normal blood pressures, but not body mass index, are risk factors for the subsequent occurrence of both preeclampsia and gestational hypertension : A retrospective cohort study
Authors: Ohkuchi, Akihide Browse this author
Iwasaki, Ryuhiko Browse this author
Suzuki, Hirotada Browse this author
Hirashima, Chikako Browse this author
Takahashi, Kayo Browse this author
Usui, Rie Browse this author
Matsubara, Shigeki Browse this author
Minakami, Hisanori Browse this author →KAKEN DB
Suzuki, Mitsuaki Browse this author
Keywords: gestational hypertension
high-normal blood pressure
hypertension
obesity
preeclampsia
Issue Date: Mar-2006
Publisher: JAPANESE SOC HYPERTENSION
Journal Title: Hypertension research
Volume: 29
Issue: 3
Start Page: 161
End Page: 167
Publisher DOI: 10.1291/hypres.29.161
Abstract: Blood pressure (BP) levels and body mass index (BMI) are known as risk factors for preeclampsia and gestational hypertension. However, there have been few investigations regarding the effects of BID and BMI levels on preeclampsia and gestational hypertension in the same cohort. In the present study, we conducted a retrospective cohort study using multiple logistic regression analysis. The cohort included 1,518 patients without nephritis. The unadjusted odds ratios (ORs) of preeclampsia and gestational hypertension were increased in pregnant women with normal BP (120-129 mmHg systolic or 80-84 mmHg diastolic), high-normal BID and hypertension in the second trimester compared to those with optimal BP. The unadjusted ORs of preeclampsia and gestational hypertension were also increased in obese women in the pre-pregnancy period compared to women with normal range BML When adjustment was made for both the BP levels and pre-pregnancy BMI levels, the ORs (95% confidence intervals) of normal BID, high-normal BID, hypertension and obesity for the subsequent occurrence of preeclampsia were 5.1 (2.2-12), 8.3 (3.1-22), 16 (5.0-50) and 2.0 (0.67-5.9), and those for the subsequent occurrence of gestational hypertension were 7.0 (2.6-19), 7.4 (2.1-25), 22 (6.1-83) and 1.3 (0.33-4.8), respectively. For the subsequent occurrence of preeclampsia or gestational hypertension, normal BID, high-normal BP and hypertension in the second trimester may be independent risk factors. Obesity in the pre-pregnancy period, however, may not be an independent risk factor.
Rights: Hypertension Research (Vol. 29(3). p. 161-167)からの転載
Relation: http://www.jpnsh.org/
Type: article
URI: http://hdl.handle.net/2115/11364
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 水上 尚典

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