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Influence of intravenous sedation with midazolam on Respiratory function and muscle activity inelderly and young patients

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タイトル: Influence of intravenous sedation with midazolam on Respiratory function and muscle activity inelderly and young patients
著者: Fujisawa, Toshiaki 著作を一覧する
Suzuki, Shinobu 著作を一覧する
Kurozumi, Akihiro 著作を一覧する
Kimura, Yukifumi 著作を一覧する
Iida, Akira 著作を一覧する
Fukushima, Kazuaki 著作を一覧する
キーワード: Aged
Sedative
nonbarbiturate
Respiratory muscles
Hand strength
発行日: 2002年12月 1日
出版者: Scientific
誌名: The Asian Journal of Oral and Maxillofacial Surgery
巻: 14
号: 4
開始ページ: 209
終了ページ: 214
抄録: Objective: The purpose of this study was to investigate the optimal dosage of intravenous midazolam for sedation in elderly patients and compare the amount of depression of respiratory function and skeletal muscle activity after obtaining similar sedation levels in younger patients. Patients and Methods: Fifteen elderly patients older than 65 years (group E) and 15 patients younger than 55 years (group Y) underwent oral surgery or dental treatment with or without local anaesthesia after intravenous administration of midazolam. Results: The optimal dose for the elderly patients was 62% that for the younger patients. The duration of depression of arterial oxygen saturation and vital capacity was more prolonged among patients in group E than in those in group Y. The number of patients whose grip strength value recovered 15 and 30 minutes after administration of midazolam was significantly smaller for group E than for group Y. Conclusion: These results suggest that elderly people should be carefully treated with attention to the decrease in skeletal muscle activity, including respiratory and upper airway muscles, when receiving intravenous sedation with midazolam.
Rights: © Asian Journal of Oral and Maxillofacial Surgery
Relation (URI): http://www.asianaoms.org/asianjournal.html
資料タイプ: article
URI: http://hdl.handle.net/2115/11367
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 藤澤 俊明

 

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