HUSCAP logo Hokkaido Univ. logo

Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >

Resection of lung metastasis from gallbladder carcinoma: immunohistochemistry of RCASI and CD8(+)T cells in primary and metastatic tumors

Files in This Item:
oshikiri.pdf1.3 MBPDFView/Open
Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/14474

Title: Resection of lung metastasis from gallbladder carcinoma: immunohistochemistry of RCASI and CD8(+)T cells in primary and metastatic tumors
Authors: Oshikiri, Taro1 Browse this author
Morita, Takayuki Browse this author
Fujita, Miyoshi Browse this author
Miyasaka, Yuji Browse this author
Senmaru, Naoto Browse this author
Yamada, Hidehisa Browse this author
Kaji, Naoto Browse this author
Kondo, Satoshi8 Browse this author →KAKEN DB
Authors(alt): 押切, 太郎1
近藤, 哲8
Keywords: immunohistochemistry
CD8 T cells
thyroid transcription factor 1
RCAS1
Issue Date: 8-May-2006
Publisher: Elsevier Ireland
Journal Title: Cancer letters
Volume: 237
Issue: 1
Start Page: 115
End Page: 122
Publisher DOI: 10.1016/j.canlet.2005.05.050
Abstract: Advanced Gallbladder cancer has an extremely poor prognosis. We examined a patient with resectable gallbladder cancer with associated lung metastasis. A 64-year-old female patient, diagnosed with gallbladder cancer and a solitary benign lung tumor by imaging, was subjected to extensive cholecystectomy and extrahepatic bile duct resection. After one year, a follow-up CT indicated enlargement of the lung tumor; video-assisted right middle lobectomy was then performed. The lung tumor was diagnosed as a metastasis derived from the gallbladder cancer by pathology and immunohistochemistry. Expression of RCAS1, an independent unfavorable prognostic indicator in gallbladder cancer, was observed in both the gallbladder and lung tumors. However, infiltration of CD8+T cells was only seen in the lung metastatic tumor. She has remained free of any evidence of recurrence in the 10 months and 4 years after the first surgery. The results that metastasis is solitary and infiltrated by CD8+T cells correspond with the present clinical history.
Relation: http://www.sciencedirect.com/science/journal/03043835
Type: article (author version)
URI: http://hdl.handle.net/2115/14474
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 押切 太郎

Export metadata:

OAI-PMH ( junii2 , jpcoar )

MathJax is now OFF:


 

 - Hokkaido University