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Burkholderia pickettii spondylitis

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Title: Burkholderia pickettii spondylitis
Authors: Sudo, Hideki Browse this author
Hisada, Y. Browse this author
Ito, M. Browse this author
Kotaki, H. Browse this author
Minami, A. Browse this author
Keywords: Burkholderia pickettii
Issue Date: Aug-2005
Publisher: Nature Publishing Group
Journal Title: Spinal Cord
Volume: 43
Issue: 8
Start Page: 499
End Page: 502
Publisher DOI: 10.1038/
PMID: 15867939
Abstract: Methods: A 48-year-old woman presented with a complaint of severe back pain radiating from the right side of her chest. Plain radiographs of the spine showed osteolytic destruction of the right side of the T10 vertebral body at T10 level, with an involvement of the pedicle. Magnetic resonance image of the spine showed a low signal intensity from the T10 vertebral body on a Tl-weighted image and an increased signal intensity on T2-weighted sequence image. These lesions were enhanced when a contrast medium was used. The patient underwent open biopsy and specimens were collected through the right pedicle. Results: Diagnosis was established on the basis of direct identification of the microorganism. Histological findings were consistent with examination of B. pickettii spondylitis. Chemotherapy (intravenous cefepime and per os minocycline) resulted in complete cure. Conclusion: B. pickettii is widely distributed in aqueous sources in nature and has not previously been considered to be an aggressive pathogen towards humans. This case report will help to improve our understanding of the ecology and virulent pathogenicity of this organism. A biopsy is an essential and reliable method for the early etiologic diagnosis, which will lead to prevent the development of more severe complications such as spinal cord compression.
Rights: Nature Publishing Group, Spinal Cord, vol. 43, 2005, 499-502
Type: article
Appears in Collections:北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 須藤 英毅

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