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Oral administration of freeze-dried kefir reduces intestinal permeation of and oral sensitization to ovalbumin in mice

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Title: Oral administration of freeze-dried kefir reduces intestinal permeation of and oral sensitization to ovalbumin in mice
Authors: Umeda, Chisato Browse this author
Sonoyama, Kei Browse this author →KAKEN DB
Yamaguchi, Natsu Browse this author
Saito, Ryo Browse this author
Akashi, Keiko Browse this author
Motoshima, Hidemasa Browse this author
Kawabata, Jun Browse this author →KAKEN DB
Keywords: kefir
ovalbumin
gastrointestinal permeation
oral sensitization
BALB/c mice
Issue Date: Jan-2005
Publisher: 日本農芸化学会
Journal Title: Bioscience Biotechnology and Biochemistry
Volume: 69
Issue: 1
Start Page: 249
End Page: 251
Publisher DOI: 10.1271/bbb.69.249
PMID: 15665499
Abstract: An increase in plasma ovalbumin concentrations after intragastric administration of ovalbumin was suppressed by concomitant freeze-dried kefir in BALB/c mice. Serum levels of ovalbumin-specific immunoglobulin G and proliferation of splenic mononuclear cells in mice immunized orally with ovalbumin were suppressed by feeding freeze-dried kefir. We propose that kefir reduces intestinal permeation of food antigen, which contributes to suppression of oral sensitization.
Relation: http://www.jstage.jst.go.jp/
Type: article
URI: http://hdl.handle.net/2115/14829
Appears in Collections:農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 園山 慶

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