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A new dynamic myocardial phantom for the assessment of left ventricular function by gated single-photon emission tomography.
Title: | A new dynamic myocardial phantom for the assessment of left ventricular function by gated single-photon emission tomography. |
Authors: | Kubo, Naoki Browse this author →KAKEN DB | Morita, Koichi Browse this author | Katoh, Chietsugu Browse this author | Shiga, Tohru Browse this author | Konno, Masanori Browse this author | Tsukamoto, Eriko Browse this author | Morita, Yutaka Browse this author | Tamaki, Nagara Browse this author |
Keywords: | Myocardium | Phantom | Wall motion | Single-photon emission tomography |
Issue Date: | Sep-2000 |
Journal Title: | European Journal of Nuclear Medicine and Molecular Imaging |
Volume: | 27 |
Issue: | 10 |
Start Page: | 1525 |
End Page: | 1530 |
Publisher DOI: | 10.1007/s002590000318 |
PMID: | 11083542 |
Abstract: | Gated myocardial perfusion single-photon emission tomography (SPET) has been used for the measurement of left ventricular (LV) function and validated by means of comparison with other imaging modalities. We have designed a new dynamic myocardial phantom in order to validate the LV function as assessed by the use of gated myocardial perfusion SPET. The phantom consists of two half-ellipsoids (an endocardial surface and an epicardial surface) and a thorax. The myocardial space is filled with a radioactive solution. The endocardial surface moves continuously towards and away from the epicardial surface in the longitudinal axis to vary the LV volume [143 ml at end-diastole (ED), 107 ml at end-systole (ES)] and thickness (apex 8 mm at ED and 26 mm at ES, midplane 8 mm). The mean values of wall motion (WM) for the apical midplane region and the basal midplane region were 5 mm and 2 mm, respectively. Gated myocardial SPET was performed during 8 and 16 intervals. These projection data sets were processed using a Butterworth filter with an order of 5 and a critical frequency of 0.34 cycles/cm. LV function was calculated using the quantitative gated SPET (QGS) algorithm. The LV function values estimated by gated SPET during 16 intervals [22% for ejection fraction (EF), 3.7 mm for WM of the apical midplane, 1.7 mm for WM of the basal midplane] closely resembled actual LV functions [25% for EF, 5 mm for WM of the apical midplane, 2 mm for WM of the basal midplane]. However, the estimated values during 8 intervals were smaller than those during 16 intervals (19% for EF, 3.3 mm for WM of the apical-midplane, 1.1 mm for WM of the basal-midplane). The estimated LV volumes closely correlated with the actual volumes (r=0.99 for 16 intervals, r=0.95 for 8 intervals). Utilizing this phantom, LV function estimated using gated myocardial SPET can be compared with actual values. |
Rights: | The original publication is available at www.springerlink.com |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/14887 |
Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 久保 直樹
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