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Complete cDNA Sequences and Phylogenetic Analyses of the Th1 and Th2 Cytokines of the Bactrian Camel (Camelus bactrianus)

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タイトル: Complete cDNA Sequences and Phylogenetic Analyses of the Th1 and Th2 Cytokines of the Bactrian Camel (Camelus bactrianus)
著者: Odbileg, Raadan 著作を一覧する
Purevtseren, Byambaa 著作を一覧する
Batsukh, Zayat 著作を一覧する
Konnai, Satoru 著作を一覧する
Ohashi, Kazuhiko 著作を一覧する
Onuma, Misao 著作を一覧する
キーワード: camel cytokines
cDNA sequence
phylogenetic analysis
Th1
Th2
発行日: 2006年 9月
出版者: Japanese Society of Veterinary Science
誌名: Journal of Veterinary Medical Science
巻: 68
号: 9
開始ページ: 941
終了ページ: 946
出版社 DOI: 10.1292/jvms.68.941
抄録: The complementary DNAs of the Th1 (IL-2, IL-12p35, and IFN-γ) and Th2 (IL-4, IL-10 and IL-13) cytokine genes of the bactrian camel (Camelus bactrianus) were cloned, sequenced, and analyzed. IL-2, IL-4, IL-10, IL-12p35, IL-13, and IFN-γ were found to have 465, 402, 537, 669, 411, and 501 bp length open reading frames with 154, 133, 178, 222, 136, and 166 amino acid encodings, respectively. The homology ranged from 58.8% to 100% between the nucleotide sequences of the camel cytokine genes and the published sequences of other mammalian genes, including the llama, pig, cow, horse, human, and mouse. The cDNA had highest homology with orders Artiodactyla (pigs and cattle) and Perissodactyla (horses), especially to the recently cloned llama sequences.
資料タイプ: article (author version)
URI: http://hdl.handle.net/2115/15849
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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