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Complete cDNA Sequences and Phylogenetic Analyses of the Th1 and Th2 Cytokines of the Bactrian Camel (Camelus bactrianus)

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Title: Complete cDNA Sequences and Phylogenetic Analyses of the Th1 and Th2 Cytokines of the Bactrian Camel (Camelus bactrianus)
Authors: Odbileg, Raadan Browse this author
Purevtseren, Byambaa Browse this author
Batsukh, Zayat Browse this author
Konnai, Satoru Browse this author →KAKEN DB
Ohashi, Kazuhiko Browse this author →KAKEN DB
Onuma, Misao Browse this author →KAKEN DB
Keywords: camel cytokines
cDNA sequence
phylogenetic analysis
Th1
Th2
Issue Date: Sep-2006
Publisher: Japanese Society of Veterinary Science
Journal Title: Journal of Veterinary Medical Science
Volume: 68
Issue: 9
Start Page: 941
End Page: 946
Publisher DOI: 10.1292/jvms.68.941
PMID: 17019063
Abstract: The complementary DNAs of the Th1 (IL-2, IL-12p35, and IFN-γ) and Th2 (IL-4, IL-10 and IL-13) cytokine genes of the bactrian camel (Camelus bactrianus) were cloned, sequenced, and analyzed. IL-2, IL-4, IL-10, IL-12p35, IL-13, and IFN-γ were found to have 465, 402, 537, 669, 411, and 501 bp length open reading frames with 154, 133, 178, 222, 136, and 166 amino acid encodings, respectively. The homology ranged from 58.8% to 100% between the nucleotide sequences of the camel cytokine genes and the published sequences of other mammalian genes, including the llama, pig, cow, horse, human, and mouse. The cDNA had highest homology with orders Artiodactyla (pigs and cattle) and Perissodactyla (horses), especially to the recently cloned llama sequences.
Type: article (author version)
URI: http://hdl.handle.net/2115/15849
Appears in Collections:獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 今内 覚

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