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Results of radical distal pancreatectomy with en bloc resection of the celiac artery for locally advanced cancer of the pancreatic body.

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Title: Results of radical distal pancreatectomy with en bloc resection of the celiac artery for locally advanced cancer of the pancreatic body.
Authors: Kondo, Satoshi Browse this author
Katoh, Hiroyuki Browse this author
Hirano, Satoshi Browse this author
Ambo, Yoshiyasu Browse this author
Tanaka, Eiichi Browse this author
Okushiba, Shunichi Browse this author
Morikawa, Toshiaki Browse this author
Keywords: Pancreatic cancer
Distal pancreatectomy
Celiac artery resection
Hepatic artery resection
Portal vein resection
Issue Date: Apr-2003
Publisher: Springer
Journal Title: Langenbeck s Archives of Surgery
Volume: 388
Issue: 2
Start Page: 101
End Page: 106
Publisher DOI: 10.1007/s00423-003-0375-5
PMID: 12684805
Abstract: Background Locally advanced cancer of the pancreatic body involving the celiac and/or common hepatic arteries is often considered unresectable. Radical distal pancreatectomy with en bloc resection of these arteries without reconstruction was recently introduced to treat these tumors. However, experience is still limited. This study reviewed the safety and utility of the operation. Patients and methods We retrospectively studied the charts of 13 patients who underwent radical distal pancreatectomy. Results Unplanned arterial reconstruction was required in three patients due to accidental injury. The postoperative mortality rate was 0% despite a morbidity rate of 62%. Patient's intractable abdominal and/or back pain was completely relieved immediately after surgery. Contrary to expectations, postoperative diarrhea was mild. The surgical margins, including the retroperitoneum, were clear histologically (R0 resection) in all patients. The 1- and 2-year survival rates were 51% and 14%, respectively, and median survival was 12.2 months. The site of recurrence was the liver in six patients and retroperitoneum in one. Conclusions Distal pancreatectomy with en bloc resection of the celiac artery is feasible and safe, offers a high resectability rate, and has dramatic analgesic effect. Local control of disease is excellent despite frequent hepatic recurrence.
Rights: The original publication is available at www.springerlink.com
Type: article (author version)
URI: http://hdl.handle.net/2115/15853
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 近藤 哲

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